Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.72 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.72 |
| ▸ | PDE4A | P27815 | 12/20 | 0.72 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464942 | 1.00 | PDE4D (0.72) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL19155555 | 1.00 | PDE4D (0.72) | PDE4DPDE4BPDE4APDE4C | |
| Hydrochloric Acid SCHEMBL4013065 | 0.99 | PDE4D (0.71) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6027642 | 0.90 | PDE4D (0.74) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL4010319 | 0.88 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2889194 | 0.88 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6467291 | 0.87 | PDE4D (0.74) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2886831 | 0.87 | PDE4D (0.74) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7061325 | 0.87 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2887475 | 0.87 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004098633-A1 | COMPOSITION COMPRISING A PDE-4 INHIBITOR AND A TNF ALPHA ANTAGONIST | ALTANA PHARMA AG (DE) | 2004-11-18 | — | — | WO | disclosed |