Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.61 |
| ▸ | PDE4A | P27815 | 9/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.61 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887475 | 1.00 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| Hydrochloric Acid SCHEMBL4011484 | 0.99 | PDE4D (0.61) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL19155555 | 0.87 | PDE4D (0.72) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6725922 | 0.87 | PDE4D (0.72) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL464942 | 0.87 | PDE4D (0.72) | PDE4DPDE4BPDE4APDE4C | |
| Hydrochloric Acid SCHEMBL4013065 | 0.86 | PDE4D (0.71) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6417338 | 0.85 | PDE4B (0.56) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL6031473 | 0.81 | PDE4D (0.60) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6031471 | 0.81 | PDE4D (0.60) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2889194 | 0.81 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482938-A1 | PHARMACEUTICAL COMPOSITION OF A PDE4 OR A PDE3/4 INHIBITOR AND A HISTAMINE RECEPTOR ANTAGONIST | ALTANA Pharma AG (DE) | 2004-12-08 | — | — | EP | claimed |
| WO-2003074055-A1 | PHARMACEUTICAL COMPOSITION OF A PDE4 OR A PDE3/4 INHIBITOR AND A HISTAMINE RECEPTOR ANTAGONIST | ALTANA PHARMA AG (DE) | 2003-09-12 | — | — | WO | claimed |