Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896908 | 0.89 | LMNA (0.39) | LMNACYP2C9 | |
| SCHEMBL445090 | 0.81 | LMNA (0.37) | LMNACYP2C9PRKCA | |
| SCHEMBL48742 | 0.77 | TSHR (0.41) | HPGDTSHRTHRB | |
| SCHEMBL1897225 | 0.77 | MEN1 (0.36) | HPGDTSHRPRKCA | |
| SCHEMBL12902854 | 0.77 | HPGD (0.34) | HPGDTSHR | |
| SCHEMBL1481810 | 0.76 | LMNA (0.46) | LMNACYP2C9 | |
| SCHEMBL1481813 | 0.76 | LMNA (0.46) | LMNACYP2C9 | |
| SCHEMBL2938659 | 0.75 | TSHR (0.39) | HPGDTSHRTHRB | |
| SCHEMBL28511815 | 0.73 | TSHR (0.38) | HPGDTSHRTHRB | |
| SCHEMBL5154743 | 0.73 | TSHR (0.38) | HPGDTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677419-B1 | REACTING STOICHIOMETRIC EXCESS OF UNSATURATED ALICYCLIC MONOMER WITH ANOTHER UNSATURATED MONOMER, HAVING LESS THAN TWO ELECTRON-WITHDRAWING GROUPS APPENDED TO UNSATURATION, IN PRESENCE OF FREE RADICAL INITIATOR | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2004-01-13 | — | — | US | disclosed |