SCHEMBL6726044

SCHEMBL6726044

O=C(c1ccc(-c2ccncc2)[nH]c1=O)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F10 P00742 13/20 0.54
ATM Q13315 1/20 0.53
LMNA P02545 2/20 0.49
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.49
PKM P14618 1/20 0.49
F2 P00734 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6728607 0.88 F10 (0.49) F10LMNAALDH1A1KDM4EPKM
SCHEMBL6735877 0.86 F10 (0.54) F10ALDH1A1
SCHEMBL6736047 0.85 F10 (0.54) F10ALDH1A1F2
SCHEMBL5733495 0.84 ATM (0.58) F10ATMLMNAALDH1A1F2
SCHEMBL6198847 0.81 F10 (0.55) F10ATMLMNAALDH1A1F2
SCHEMBL6198681 0.81 F10 (0.55) F10ATMLMNAALDH1A1F2
Hydrochloric Acid SCHEMBL6197321 0.81 F10 (0.55) F10ATMLMNAALDH1A1F2
Hydrochloric Acid SCHEMBL6196916 0.81 F10 (0.54) F10ATMLMNAALDH1A1F2
SCHEMBL5193868 0.81 ATM (0.71) F10ATMLMNAF2SMN1; SMN2
Hydrochloric Acid SCHEMBL6200516 0.80 F10 (0.58) F10ATMLMNAALDH1A1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 F10 19/4885ATM 2080/4885LMNA 1760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.