Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156759 | 0.68 | ALDH1A1 (0.32) | ALDH1A1TDP1LMNAMAPTHTT | |
| SCHEMBL4522415 | 0.64 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7821731 | 0.61 | CFTR (0.37) | ALDH1A1TDP1LMNACRHBPCRHR2 | |
| SCHEMBL6205053 | 0.61 | — | — | |
| Biphenyl SCHEMBL27380379 | 0.60 | ALDH1A1 (0.75) | ALDH1A1TDP1LMNACRHBPCRHR2 | |
| Biphenyl SCHEMBL27480125 | 0.60 | ALDH1A1 (0.71) | ALDH1A1TDP1LMNACRHBPCRHR2 | |
| Biphenyl SCHEMBL9403462 | 0.60 | ALDH1A1 (0.84) | ALDH1A1TDP1LMNACRHBPCRHR2 | |
| Biphenyl SCHEMBL6919136 | 0.58 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNACRHBPCRHR2 | |
| Biphenyl SCHEMBL27821216 | 0.58 | CRHBP (0.56) | ALDH1A1TDP1LMNACRHBPCRHR2 | |
| SCHEMBL25187033 | 0.58 | MAPK1 (0.74) | ALDH1A1TDP1LMNACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677163-B1 | SIMPLE AND DURABLE IMMOBILIZATION OF BIOMOLECULES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2004-01-13 | — | — | US | disclosed |