SCHEMBL6726595

SCHEMBL6726595

O=C(c1cnc(-c2cccc(CO)[n+]2[O-])nc1)N1CCN(S(=O)(=O)c2nc3cc(Cl)ccc3[nH]2)CC1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F10 P00742 10/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
LMNA P02545 2/20 0.38
KLK1 P06870 1/20 0.38
GAA P10253 2/20 0.37
OPRM1 P35372 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6726600 0.94 HRH4 (0.39) F10L3MBTL1LMNAKLK1GAA
SCHEMBL6725166 0.93 F10 (0.38) F10L3MBTL1LMNAKLK1GAA
SCHEMBL6728633 0.90 F10 (0.45) F10L3MBTL1LMNAKLK1GAA
SCHEMBL6731422 0.90 L3MBTL1 (0.41) F10L3MBTL1LMNAKLK1GAA
SCHEMBL6730953 0.89 GAA (0.37) F10L3MBTL1LMNAKLK1GAA
SCHEMBL6725174 0.87 F10 (0.40) F10L3MBTL1LMNAKLK1GAA
SCHEMBL6734267 0.87 F10 (0.54) F10KLK1OPRM1
SCHEMBL6729063 0.86 F10 (0.41) F10L3MBTL1LMNAKLK1GAA
SCHEMBL6725353 0.86 F10 (0.41) F10L3MBTL1LMNAKLK1GAA
SCHEMBL6728941 0.84 F10 (0.49) F10L3MBTL1LMNAGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 F10 19/4885L3MBTL1 274/4885LMNA 1760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.