Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 11/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6726499 | 0.96 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8328720 | 0.94 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6722727 | 0.93 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6715791 | 0.93 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6718315 | 0.93 | MEN1 (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6726592 | 0.92 | MEN1 (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6719557 | 0.92 | KMT2A (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6726353 | 0.91 | MEN1 (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6719603 | 0.90 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6718706 | 0.90 | MEN1 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | SLC1A2, SLC1A1, SLC7A11 | ALDH1A1 575/4885SMN1; SMN2 2115/4885MEN1 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.