Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 11/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.62 |
| ▸ | LMNA | P02545 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6726499 | 0.95 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6726682 | 0.94 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6726773 | 0.93 | MEN1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6722727 | 0.92 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6715791 | 0.92 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6718315 | 0.92 | MEN1 (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6719654 | 0.92 | MEN1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6726961 | 0.92 | MEN1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6719353 | 0.92 | MEN1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL8334611 | 0.91 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |