Sugi Predict

Sugi Predict / Compounds / SCHEMBL6726809

SCHEMBL6726809

SCHEMBL6726809

CN(c1cc(-c2ccccc2)cc(-c2ccccc2)c1)c1cccc(-c2ccccc2-c2ccccc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHKA P35790 3/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ NPY1R P25929 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ PDK2 Q15119 1/20 0.37
▸ ABCG2 Q9UNQ0 1/20 0.35
▸ PDE5A O76074 2/20 0.35
▸ PTGER1 P34995 1/20 0.35
▸ PTGER4 P35408 1/20 0.35
▸ PTGER3 P43115 1/20 0.35
▸ PTGER2 P43116 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6723847 0.93 CHKA (0.42) CHKAMEN1KMT2ASMN1; SMN2MAPK1
SCHEMBL6723965 0.91 CHKA (0.45) CHKAMEN1KMT2ASMN1; SMN2PDK2
SCHEMBL6723811 0.89 PDK2 (0.43) CHKAMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL6723966 0.89 PDK2 (0.43) CHKAMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL6723996 0.89 CHKA (0.46) CHKAABCG2PDE5A
SCHEMBL6724123 0.89 CHKA (0.46) CHKAABCG2PDE5A
SCHEMBL6723990 0.87 MEN1 (0.43) CHKAMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL6724025 0.87 CHKA (0.45) CHKAMEN1KMT2AABCG2PDE5A
SCHEMBL6724083 0.86 MEN1 (0.42) CHKAMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL6723913 0.85 CHKA (0.49) CHKAMEN1KMT2AABCG2PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178216-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 — — US disclosed
US-8178216-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 — — US disclosed
US-20090072718-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-19 — — US disclosed
US-20090072718-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090072718-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative CRY1, GRK1, CRY2 CHKA 4185/4885MEN1 974/4885KMT2A 1322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.