Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640775 | 0.98 | PNMT (0.33) | PNMT | |
| SCHEMBL27669501 | 0.97 | PNMT (0.32) | PNMT | |
| Hydrochloric Acid SCHEMBL6726900 | 0.96 | PNMT (0.32) | PNMT | |
| SCHEMBL27941468 | 0.95 | PNMT (0.31) | PNMT | |
| Hydrochloric Acid SCHEMBL6295596 | 0.84 | PNMT (0.33) | PNMT | |
| Hydrochloric Acid SCHEMBL6557762 | 0.82 | PNMT (0.33) | PNMT | |
| SCHEMBL7560364 | 0.82 | PNMT (0.35) | PNMT | |
| SCHEMBL6557648 | 0.81 | PNMT (0.34) | PNMT | |
| Hydrochloric Acid SCHEMBL27331225 | 0.81 | PNMT (0.34) | PNMT | |
| SCHEMBL27669413 | 0.81 | PNMT (0.34) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746981-B2 | OLEFIN POLYMERIZATION CATALYSTS WITH PRODUCTIVITY WHEN FRESH OF >/= 18,000 GRAMS OF POLYETHYLENE PER GRAM OF CATALYST IN ONE HOUR, AND A SPECIFIC SURFACE AREA OF </= 20 M2/G | ALBEMARLE CORPORATION | 2004-06-08 | — | — | US | disclosed |
| US-6730758-B2 | ADDITION POLYMERIZATION OF ALPHA-OLEFIN HYDROCARBON IN PRESENCE OF SELF-SUPPORTED VINYLOLEFIN-PREPOLYMERIZED CATALYST | ALBEMARLE CORPORATION | 2004-05-04 | — | — | US | disclosed |
| EP-1037931-B1 | CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY | ALBEMARLE CORP (US) | 2004-02-04 | — | — | EP | disclosed |
| US-6677265-B1 | THE METALLOCENE USED AS THE FEED HAVING IN THE MOLECULE AT LEAST ONE POLYMERIZABLE OLEFINIC SUBSTITUENT | ALBEMARLE CORPORATION | 2004-01-13 | — | — | US | disclosed |
| US-20030191254-A1 | PARTICULATE GROUP 4 METALLOCENE-ALUMINOXANE CATALYST COMPOSITIONS DEVOID OF PREFORMED SUPPORT, AND THEIR PREPARATION AND THEIR USE | ALBEMARLE CORPORATION | 2003-10-09 | — | — | US | disclosed |
| US-20030105253-A1 | Particulate group 4 metallocene-aluminoxane catalyst compositions devoid of preformed support, and their preparation and their use | ALBEMARLE CORPORATION | 2003-06-05 | — | — | US | disclosed |
| US-6551955-B1 | Olefin polymerization catalysts; efficiency | ALBEMARLE CORPORATION | 2003-04-22 | — | — | US | disclosed |
| US-6521728-B1 | Particulate group 4 metallocene-aluminoxane catalyst compositions devoid of preformed support, and their preparation and their use | ALBEMARLE CORPORATION | 2003-02-18 | — | — | US | disclosed |
| US-6294496-B1 | VERY HIGH PRODUCTIVITIES; PREPOLYMERIZING VINYLOLEFIN WITH A GROUP 4 METALLOCENE-ALUMINOXANE SOLUTION | ALBEMARLE CORPORATION | 2001-09-25 | — | — | US | disclosed |