SCHEMBL672697

SCHEMBL672697

CC1=Cc2c(cccc2C(C)(C)C)C1[Zr](Cl)(Cl)(C1C(C)=Cc2c1cccc2C(C)(C)C)[SiH](C)C

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7198216 0.85
SCHEMBL5352527 0.84 GABRA1 (0.31) GABRA1GABRB2CA2
SCHEMBL389032 0.82
SCHEMBL5609134 0.82
SCHEMBL5003188 0.81
SCHEMBL6234373 0.80 GABRA1 (0.30) GABRA1GABRB2CA2
SCHEMBL5609483 0.80
SCHEMBL5003545 0.79
SCHEMBL5003490 0.79
SCHEMBL273374 0.79 BRD4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 EP claimed
EP-1058694-B1 Catalyst system, method for its production and its use for the polymerisation of olefins BASELL POLYOLEFINE GMBH (DE) 2003-04-09 EP claimed
US-6482902-B1 Catalyst system TARGOR GMBH (DE) 2002-11-19 US claimed
US-6391989-B1 COORDINATION CATALYST ON SUPPORT; POLYMERIZATION OF ALPHA-OLEFINS BASELL POLYPROPYLEN GMBH (DE) 2002-05-21 US claimed
US-5278264-A Catalytic polymerizing in presence of a transition metal metallocene HOECHST AG (DE) 1994-01-11 US claimed
EP-1648946-B1 OLEFIN POLYMERIZATION PROCESS BASELL POLYOLEFINE GMBH (DE) 2015-07-15 EP disclosed
WO-2014070655-A1 SUPPORTED METALLOCENE CATALYST SYSTEMS AND METHODS OF PREPARATION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-05-08 WO disclosed
US-20140121341-A1 Supported Metallocene Catalyst Systems and Methods of Preparation Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2014-05-01 US disclosed
US-8383731-B2 Polypropylene-based adhesive compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-02-26 US disclosed
US-8058350-B2 Polypropylene composition Basell Poliolefine Italia, s.r.l. (IT) 2011-11-15 US disclosed
EP-1680468-B1 POLYPROPYLENE COMPOSITION BASELL POLIOLEFINE SRL (IT) 2011-08-17 EP disclosed
US-20090156729-A1 Polypropylene-Based Adhesive Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2009-06-18 US disclosed
US-5614455-A Olefin polymerization catalyst, process for its preparation, and its use HOECHST AKTIENGESELLSCHAFT (DE) 1997-03-25 US disclosed
US-5578537-A Olefin polymerization catalyst process for its preparation and its use HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-26 US disclosed
WO-1996034002-A1 ENHANCED SYNTHESIS OF RACEMIC METALLOCENES ALBEMARLE CORPORATION (US) 1996-10-31 WO disclosed
US-5556997-A Enhanced synthesis of racemic metallocenes ALBEMARLE CORPORATION (US) 1996-09-17 US disclosed
US-5329033-A Metallocene catalyst, indene containing ligands, alumoxane cocatalyst HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-12 US disclosed
EP-0578838-A1 Olefin polymerization catalyst, process for its preparation, and its use HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-19 EP disclosed
US-5278264-A Catalytic polymerizing in presence of a transition metal metallocene HOECHST AG (DE) 1994-01-11 US disclosed
EP-0567952-A1 Olefin polymerization catalyst, process for its preparation, and its use HOECHST AKTIENGESELLSCHAFT (DE) 1993-11-03 EP disclosed