SCHEMBL6727430

SCHEMBL6727430

C=CCCC/C=C/CCC/C=C/CCCCC=C

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 3/20 0.47
MAPT P10636 2/20 0.42
ABCC4 O15439 1/20 0.42
TRPA1 O75762 3/20 0.40
LPAR3 Q9UBY5 2/20 0.36
LMNA P02545 2/20 0.36
LPAR2 Q9HBW0 1/20 0.36
USP2 O75604 1/20 0.35
CYP3A4 P08684 1/20 0.35
RECQL P46063 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TRPV1 Q8NER1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6727431 1.00 TSHR (0.50) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL25172379 1.00 TSHR (0.50) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL25178942 0.97 TSHR (0.55) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL1273815 0.97 TSHR (0.55) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL25185246 0.97 TSHR (0.55) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL25178144 0.97 TSHR (0.55) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL5436307 0.96 TSHR (0.53) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL6731503 0.96 ALDH1A1 (0.50) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL5436303 0.96 TSHR (0.53) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL6731505 0.96 ALDH1A1 (0.50) TSHRALDH1A1MAPTABCC4TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005947-B2 Modified hydrocarbon resins as fluid loss additives INGEVITY SOUTH CAROLINA, LLC (US) 2018-06-26 US disclosed
EP-3071782-A1 MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES Georgia-Pacific Chemicals LLC (US) 2016-09-28 EP disclosed
WO-2015077215-A1 MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES GEORGIA-PACIFIC CHEMICALS LLC (US) 2015-05-28 WO disclosed
US-20150136402-A1 MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES GEORGIA-PACIFIC CHEMICALS LLC (US) 2015-05-21 US disclosed
US-6677495-B1 REACTING IN A HOMOGENEOUSLY OR HETEROGENEOUSLY CATALYZED METATHESIS REACTION A HYDROCARBON MIXTURE WHICH CONTAINS CYCLOPENTENE AND ACYCLIC MONOOLEFINS, RING-SCISSION METATHESIS AND THEIR USE AS INTERMEDIATES BASF AKTIENGESELLSCHAFT (DE) 2004-01-13 US disclosed
EP-0946469-B1 OLIGOMER MIXTURES DERIVED FROM CYCLOPENTENE, METHOD FOR THE PRODUCTION AND USE THEREOF BASF AG (DE) 2002-03-27 EP disclosed
CN-1246105-A Oligomer mixtures derived from cyclopentene, method for the production and use thereof BASF AG (DE) 2000-03-01 CN disclosed
US-4433100-A DICYCLOPENTADIENE, NON-AROMATIC UNSATURATED HYDROCARBON, FATTY OR ROSIN ACID NEVILLE CHEMICAL COMPANY (US) 1984-02-21 US disclosed