SCHEMBL6731503

SCHEMBL6731503

C=CCCC/C=C/CCCC=C

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 3/20 0.50
TRPA1 O75762 3/20 0.38
MAPT P10636 2/20 0.38
ABCC4 O15439 1/20 0.38
LMNA P02545 2/20 0.32
USP2 O75604 1/20 0.32
CYP3A4 P08684 1/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LPAR3 Q9UBY5 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6720512 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1MAPTABCC4
SCHEMBL6720513 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1MAPTABCC4
SCHEMBL6731505 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1MAPTABCC4
SCHEMBL6727430 0.96 TSHR (0.50) ALDH1A1TSHRTRPA1MAPTABCC4
SCHEMBL6727431 0.96 TSHR (0.50) ALDH1A1TSHRTRPA1MAPTABCC4
SCHEMBL25172379 0.96 TSHR (0.50) ALDH1A1TSHRTRPA1MAPTABCC4
SCHEMBL25178144 0.93 TSHR (0.55) ALDH1A1TSHRTRPA1MAPTABCC4
SCHEMBL25178942 0.93 TSHR (0.55) ALDH1A1TSHRTRPA1MAPTABCC4
SCHEMBL1273815 0.93 TSHR (0.55) ALDH1A1TSHRTRPA1MAPTABCC4
SCHEMBL25185246 0.93 TSHR (0.55) ALDH1A1TSHRTRPA1MAPTABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6677495-B1 REACTING IN A HOMOGENEOUSLY OR HETEROGENEOUSLY CATALYZED METATHESIS REACTION A HYDROCARBON MIXTURE WHICH CONTAINS CYCLOPENTENE AND ACYCLIC MONOOLEFINS, RING-SCISSION METATHESIS AND THEIR USE AS INTERMEDIATES BASF AKTIENGESELLSCHAFT (DE) 2004-01-13 US disclosed
EP-0946469-B1 OLIGOMER MIXTURES DERIVED FROM CYCLOPENTENE, METHOD FOR THE PRODUCTION AND USE THEREOF BASF AG (DE) 2002-03-27 EP disclosed
CN-1246105-A Oligomer mixtures derived from cyclopentene, method for the production and use thereof BASF AG (DE) 2000-03-01 CN disclosed
EP-0946469-A1 OLIGOMER MIXTURES DERIVED FROM CYCLOPENTENE, METHOD FOR THE PRODUCTION AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1999-10-06 EP disclosed
WO-1998028245-A1 OLIGOMER MIXTURES DERIVED FROM CYCLOPENTENE; METHOD FOR THE PRODUCTION AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1998-07-02 WO disclosed
EP-0579459-B1 Hydrosilylation process for preparation of chlorine end-terminated organosiloxanes DOW CORNING (US) 1997-05-14 EP disclosed
EP-0572183-B1 Method for preparing organofunctional polysiloxanes DOW CORNING (US) 1997-03-12 EP disclosed
US-5436308-A Cross-linked organofunctional polysiloxanes and method for preparation DOW CORNING CORPORATION (US) 1995-07-25 US disclosed
EP-0579459-A1 Hydrosilylation process for preparation of chlorine end-terminated organosiloxanes DOW CORNING CORPORATION (US) 1994-01-19 EP disclosed
EP-0572183-A1 Method for preparing organofunctional polysiloxanes DOW CORNING CORPORATION (US) 1993-12-01 EP disclosed
US-5247045-A Hydrosilylation process for preparation of novel chlorine end-terminated organosiloxanes DOW CORNING CORPORATION (US) 1993-09-21 US disclosed
US-5227448-A Method for preparing organofunctional polysiloxanes DOW CORNING CORPORATION (US) 1993-07-13 US disclosed
US-5225511-A Organofunctional polysiloxanes and method for preparation DOW CORNING CORPORATION (US) 1993-07-06 US disclosed
EP-0539065-A1 Platinum catalyzed process for preparation of alpha, omega-silylalkenes and organosiloxane copolymers DOW CORNING CORPORATION (US) 1993-04-28 EP disclosed
US-4707465-A Olefin disproportionation and catalyst therefor PHILLIPS PETROLEUM COMPANY (US) 1987-11-17 US disclosed
US-4629719-A REFRACTORY OXIDE CONTANING MOLYBOENUM OXIDE AND ELEMENTAL TIN AND MAGNESIUM PHILLIPS PETROLEUM COMPANY (US) 1986-12-16 US disclosed
US-4568788-A CATALYST MADE BY CONTACTING REFACTORY OXIDE CONTAINING MOLYDBENUM OXIDE WITH EITHER BARIUM, MAGNESIUM AND-OR TIN PHILLIPS PETROLEUM COMPANY (US) 1986-02-04 US disclosed
US-4487986-A Olefin disproportionation and catalyst therefore PHILLIPS PETROLEUM COMPANY (US) 1984-12-11 US disclosed
US-4368141-A OXIDES OF MOLYBDENUM OR TUNGSTEN TREATED WITH SULFUR PHILLIPS PETROLEUM COMPANY (US) 1983-01-11 US disclosed