Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873981 | 1.00 | KIF11 (0.40) | KIF11MAPTMAOAMAOBRXRA | |
| SCHEMBL6727412 | 0.89 | SLC6A2 (0.35) | KIF11MAPTRXRARXRBL3MBTL1 | |
| SCHEMBL18873871 | 0.89 | SLC6A2 (0.35) | KIF11MAPTRXRARXRBL3MBTL1 | |
| SCHEMBL18874115 | 0.86 | L3MBTL1 (0.36) | L3MBTL1TNKS2 | |
| SCHEMBL6727919 | 0.86 | L3MBTL1 (0.36) | L3MBTL1TNKS2 | |
| SCHEMBL6727399 | 0.85 | L3MBTL1 (0.38) | L3MBTL1TP53 | |
| SCHEMBL18873798 | 0.85 | L3MBTL1 (0.38) | L3MBTL1TP53 | |
| SCHEMBL6727686 | 0.84 | GRM2 (0.38) | KIF11MAPTL3MBTL1MCHR1 | |
| SCHEMBL18873960 | 0.84 | GRM2 (0.38) | KIF11MAPTL3MBTL1MCHR1 | |
| SCHEMBL6727333 | 0.83 | L3MBTL1 (0.36) | L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8835657-B2 | Cyclopentanedione compounds and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-8835657-B2 | Cyclopentanedione compounds and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-2010127797-A2 | CYCLOPENTANEDIONE COMPOUNDS AND THEIR USE AS INSECTICIDES, ACARICIDES AND/OR FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | WO | disclosed |
| WO-2009019015-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | CYP51A1, CYP1B1, CBR3 | KIF11 1477/4885MAPT 2942/4885MAOA 2806/4885 |
| US-20120142529-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | KIF11 3091/4885MAPT 3903/4885MAOA 2359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.