Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 4/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995547 | 0.83 | SMPD1 (0.56) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL4185332 | 0.82 | SMPD1 (0.54) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL7188026 | 0.78 | SMPD1 (0.34) | SMPD1CA2FDPS | |
| SCHEMBL4448118 | 0.77 | SMPD1 (0.44) | SMPD1CYP3A4L3MBTL1FDPSTRPM8 | |
| SCHEMBL6908494 | 0.76 | CYP3A4 (0.37) | SMPD1GGPS1CA2CYP3A4L3MBTL1 | |
| SCHEMBL29948842 | 0.75 | SMPD1 (0.38) | SMPD1GGPS1CA2FDPSTRPM8 | |
| SCHEMBL4448119 | 0.74 | SMPD1 (0.59) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL25175095 | 0.72 | CYP3A4 (0.37) | SMPD1CA2CYP3A4L3MBTL1FDPS | |
| SCHEMBL215423 | 0.72 | CYP3A4 (0.37) | SMPD1CA2CYP3A4L3MBTL1FDPS | |
| SCHEMBL672785 | 0.72 | CYP3A4 (0.37) | SMPD1CA2CYP3A4L3MBTL1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252979-A1 | Process for Producing Blends of Syndiotactic, 1,2-Polybutadiene and Rubbery Elastomers | RADEMACHER CHRISTINE (US) | 2012-10-04 | — | — | US | disclosed |
| US-8067503-B2 | Process for producing blends of syndiotactic, 1,2-polybutadiene and rubbery elastomers | BRIDGESTONE CORPORATION (JP) | 2011-11-29 | — | — | US | disclosed |