SCHEMBL6727901

SCHEMBL6727901

Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(C(=O)OC3CCCCC3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.59
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA4 P22748 2/20 0.56
CA6 P23280 2/20 0.56
CA5A P35218 2/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 2/20 0.56
CA13 Q8N1Q1 2/20 0.56
CA14 Q9ULX7 2/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
RAB9A P51151 3/20 0.56
HTT P42858 2/20 0.56
NPC1 O15118 2/20 0.56
LMNA P02545 5/20 0.55
MAPT P10636 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
PPARG P37231 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6331838 0.87 LMNA (0.54) TP53CA12CA1CA2CA4
SCHEMBL6326121 0.84 TP53 (0.62) TP53CA12CA1CA2CA4
SCHEMBL6324545 0.81 TP53 (0.54) TP53CA12CA1CA2CA4
SCHEMBL5184884 0.79 KMT2A (0.77) TP53CA12CA1CA2CA4
SCHEMBL6243996 0.79 CA12 (0.85) TP53CA12CA1CA2CA4
SCHEMBL1928662 0.79 CA12 (0.85) TP53CA12CA1CA2CA4
SCHEMBL6057098 0.79 SCN1A (0.69) SMN1; SMN2RAB9AHTTNPC1LMNA
SCHEMBL5184903 0.79 KMT2A (0.69) TP53CA12CA1CA2CA4
SCHEMBL20981688 0.78 ALDH1A1 (0.67) TP53CA12CA1CA2CA4
SCHEMBL12426775 0.78 SCN1A (0.71) SMN1; SMN2RAB9AHTTNPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1044824-B1 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO (JP) 2004-05-12 EP disclosed
US-6677472-B2 AS COLOR-DEVELOPING AGENT; HIGH WHITENESS AND RESISTANCE TO COLOR FORMATION UNDER HIGH TEMPERATURE OJI PAPER CO., LTD. (JP) 2004-01-13 US disclosed
US-6486094-B1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-11-26 US disclosed
US-20020065196-A1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-05-30 US disclosed
EP-1044824-A2 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER COMPANY LIMITED (JP) 2000-10-18 EP disclosed