Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284254 | 0.74 | PARP10 (0.49) | PARP10PARP15PARP2ALDH1A1 | |
| SCHEMBL6629777 | 0.67 | PARP10 (1.00) | PARP10PARP15PARP2ALDH1A1MAPT | |
| SCHEMBL322070 | 0.66 | PARP15 (0.78) | PARP10PARP15PARP2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL406803 | 0.65 | PARP15 (0.75) | PARP10PARP15PARP2ALDH1A1MAPT | |
| SCHEMBL6284574 | 0.65 | KCNH2 (0.49) | PARP10PARP15PARP2ALDH1A1 | |
| SCHEMBL28569301 | 0.64 | PARP10 (0.75) | PARP10PARP15PARP2ALDH1A1MAPT | |
| SCHEMBL12735790 | 0.63 | PARP10 (0.79) | PARP10PARP15PARP2CHEK2 | |
| SCHEMBL13574424 | 0.62 | MMP2 (0.63) | PARP10PARP15PARP2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL31752833 | 0.62 | PARP10 (0.77) | PARP10PARP15PARP2CHEK2 | |
| SCHEMBL24485238 | 0.62 | USP2 (0.51) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176410-A1 | 4-hydroxpiperdine derivative with analgetic activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176410-A1 | 4-hydroxpiperdine derivative with analgetic activity | HNMT, HDAC1, HDAC3 | PARP10 3017/4885PARP15 3405/4885PARP2 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.