⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224235 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL1852845 | 0.81 | — | — | |
| SCHEMBL533350 | 0.81 | — | — | |
| Acetonitrile SCHEMBL1847343 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL8956889 | 0.78 | — | — | |
| SCHEMBL3804825 | 0.78 | — | — | |
| SCHEMBL28653199 | 0.76 | — | — | |
| SCHEMBL2535365 | 0.76 | — | — | |
| SCHEMBL5408873 | 0.76 | — | — | |
| SCHEMBL18923179 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108164479-A | A kind of preparation method of dinotefuran intermediate 3- amino methyl tetrahydrofurans | 河北辉科生物技术有限公司 | 2018-06-15 | — | — | CN | claimed |
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |
| CN-111032669-B | Orthoester compositions for affinity purification of oligonucleotides | 安捷伦科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20230322742-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230122968-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2023-04-20 | — | — | US | disclosed |
| US-11548876-B2 | Orthoester compositions for affinity purification of oligonucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-11299483-B2 | Orthoester compositions for affinity purification of oligonucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2022-04-12 | — | — | US | disclosed |
| US-20200190129-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2020-06-18 | — | — | US | disclosed |
| US-20200181124-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2020-06-11 | — | — | US | disclosed |
| CN-108164479-A | A kind of preparation method of dinotefuran intermediate 3- amino methyl tetrahydrofurans | 河北辉科生物技术有限公司 | 2018-06-15 | — | — | CN | disclosed |
| EP-0493601-A1 | LIQUID-CRYSTAL COPOLYMER, PRODUCTION THEREOF, DIENE COMPOUND USED IN SAID PRODUCTION, AND PRODUCTION OF SAID COMPOUND | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0442306-A2 | (4E-cyclohexyl-3-butenyl)phenyl derivatives | F. Hoffmann-La Roche AG (CH) | 1991-08-21 | — | — | EP | disclosed |
| EP-0441213-A2 | Chiral dioxolanes | F. HOFFMANN-LA ROCHE AG (CH) | 1991-08-14 | — | — | EP | disclosed |
| US-5032312-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0410233-A2 | (4-Arylbutyl) cyclohexane derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| US-4954600-A | HIGH SPEED DISPLAY | IDEMITSU KOSAN CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0362714-A2 | Liquid-crystalline compounds and liquid-crystalline polymers | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-04-11 | — | — | EP | disclosed |
| EP-0348873-A2 | Ferroelectric liquid-crystalline polymer and epoxide usable for preparing the ferroelectric liquid-crystalline polymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-01-03 | — | — | EP | disclosed |
| US-4877858-A | FERROELECTRICAL HIG SPEED RESPONSE; DISPLAYS | IDEMETSU KOSAN CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0274128-A2 | Liquid-crystalline polymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-07-13 | — | — | EP | disclosed |