Eugenol

Eugenol

SCHEMBL6729117

C=CCc1ccc(O)c(OC)c1.Cc1ccc(C(C)C)cc1O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 13/20 0.68
ALDH1A1 P00352 3/20 0.68
PTGS1 P23219 2/20 0.68
CYP3A4 P08684 1/20 0.68
ALOX5 P09917 1/20 0.68
AR P10275 1/20 0.68
GABRA1 P14867 1/20 0.52
GABRB2 P47870 1/20 0.52
TRPA1 O75762 2/20 0.52
CACNA1C Q13936 1/20 0.51
PPARG P37231 1/20 0.50
PPARD Q03181 1/20 0.50
PPARA Q07869 1/20 0.50
FOS P01100 1/20 0.48
TTR P02766 1/20 0.48
JUN P05412 1/20 0.48
NR3C1 P04150 1/20 0.48
HSD17B1 P14061 1/20 0.48
HSD17B2 P37059 1/20 0.48
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Estragole SCHEMBL20496371 0.85 ALDH1A1 (0.56) TRPM8ALDH1A1PTGS1CYP3A4ALOX5
Carvacrol SCHEMBL25285068 0.84 PPARA (0.53) TRPM8ALDH1A1PTGS1CYP3A4ALOX5
Eugenol SCHEMBL20361 0.83 ALDH1A1 (1.00) TRPM8ALDH1A1PTGS1CYP3A4ALOX5
Eugenol SCHEMBL788240 0.83 ALDH1A1 (1.00) TRPM8ALDH1A1PTGS1CYP3A4ALOX5
Eugenol SCHEMBL29364978 0.83 ALDH1A1 (1.00) TRPM8ALDH1A1PTGS1CYP3A4ALOX5
Eugenol SCHEMBL29126189 0.83 ALDH1A1 (1.00) TRPM8ALDH1A1PTGS1CYP3A4ALOX5
Eugenol SCHEMBL21114900 0.81 ALDH1A1 (0.97) TRPM8ALDH1A1PTGS1CYP3A4ALOX5
Eugenol SCHEMBL5030243 0.81 ALDH1A1 (0.97) TRPM8ALDH1A1PTGS1CYP3A4ALOX5
Eugenol SCHEMBL25377864 0.81 ALDH1A1 (0.97) TRPM8ALDH1A1PTGS1CYP3A4ALOX5
Eugenol SCHEMBL5689917 0.81 ALDH1A1 (0.97) TRPM8ALDH1A1PTGS1CYP3A4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040248764-A1 Treatment and prevention of infections in plants EDEN RESEARCH PLC (C/O OXFORD CORPORATE SERVICES LTD.) (GB) 2004-12-09 US disclosed