Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 4/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726562 | 0.83 | BID (0.49) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL28079688 | 0.83 | BID (0.49) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL19951342 | 0.83 | BID (0.49) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL8516803 | 0.83 | BID (0.49) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL11044495 | 0.82 | KMT2A (0.62) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL11575458 | 0.79 | KMT2A (0.49) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL15200656 | 0.79 | KMT2A (0.49) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL6848551 | 0.78 | KMT2A (0.54) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL28446070 | 0.77 | KMT2A (0.53) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL38650932 | 0.75 | ALOX5 (0.38) | KMT2ATDP1L3MBTL1ESR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154981-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2004-07-21 | — | — | EP | disclosed |
| US-6676851-B1 | LOW MELTING, GOOD ALIGNMENT ARYL BRANCHED ETHER-ESTER LINKED DIACRYLATES; REMAIN STABLE DURING COATING AND CROSSLINKING | ROLIC AG (CH) | 2004-01-13 | — | — | US | disclosed |
| EP-1154981-A1 | LIQUID CRYSTAL COMPOUNDS | Rolic AG (CH) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000048985-A1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2000-08-24 | — | — | WO | disclosed |