SCHEMBL6729352

SCHEMBL6729352

CN1CCN(C2CC3CN(S(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC(C2)N3C(=O)c2ccc(-c3cc[n+]([O-])cc3)cc2)CC1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.46
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
F2 P00734 5/20 0.39
KDM2B Q8NHM5 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6734456 0.93 F10 (0.42) F10HTTL3MBTL1F2KDM2B
SCHEMBL6738164 0.92 ALDH1A1 (0.42) F10MEN1KMT2AL3MBTL1F2
SCHEMBL6729129 0.90 F10 (0.46) F10MEN1HTTKMT2AL3MBTL1
SCHEMBL6726151 0.89 F10 (0.41) F10MEN1HTTKMT2AL3MBTL1
SCHEMBL6733783 0.87 F10 (0.41) F10MEN1HTTKMT2AL3MBTL1
SCHEMBL6731450 0.87 F10 (0.41) F10MEN1HTTKMT2AL3MBTL1
SCHEMBL6731011 0.82 F10 (0.45) F10L3MBTL1F2KDM2BKDM4E
SCHEMBL6736899 0.82 F10 (0.40) F10F2
SCHEMBL6725920 0.81 F10 (0.46) F10MEN1KMT2AL3MBTL1F2
SCHEMBL6727759 0.80 F10 (0.42) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 F10 19/4885MEN1 2216/4885HTT 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.