Curcumin

Curcumin

SCHEMBL6729416

COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O.[Na]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 10/20 0.97
▸ MAPT P10636 9/20 0.97
▸ BACE1 P56817 5/20 0.97
▸ MMP9 P14780 4/20 0.97
▸ NFKB1 P19838 3/20 0.97
▸ CYP2D6 P10635 2/20 0.97
▸ CYP2C9 P11712 2/20 0.97
▸ TSHR P16473 2/20 0.97
▸ HSD17B10 Q99714 2/20 0.97
▸ ABCB1 P08183 2/20 0.97
▸ AKR1B1 P15121 2/20 0.97
▸ MAOA P21397 2/20 0.97
▸ MAOB P27338 2/20 0.97
▸ HDAC3 O15379 2/20 0.97
▸ HDAC1 Q13547 2/20 0.97
▸ HDAC2 Q92769 2/20 0.97
▸ HDAC6 Q9UBN7 2/20 0.97
▸ ALOX5 P09917 2/20 0.97
▸ STAT3 P40763 2/20 0.97
▸ NFKB2 Q00653 2/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Curcumin SCHEMBL9803318 1.00 APP (0.97) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL30298985 1.00 APP (0.97) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL6901740 0.98 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL8440 0.98 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL250984 0.98 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL8336603 0.98 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL17629819 0.98 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL2804734 0.98 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL17629818 0.98 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL29360171 0.98 APP (1.00) APPMAPTBACE1MMP9NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116963724-A Treatment for human malignant pleural effusion 萨恩帕斯药物有限公司 2023-10-27 — — CN claimed
CN-116710123-A Cytokine release and inhibition of cytokine storm 萨恩帕斯药物有限公司 2023-09-05 — — CN claimed
CN-115429775-A Preparation method of curcumin microcapsule 黄河三角洲京博化工研究院有限公司 2022-12-06 — — CN claimed
CN-106822915-A A kind of curcumin hyaluronic acid nanometer micella for treating rheumatoid arthritis and its preparation method and application 兰州大学 2017-06-13 — — CN claimed
CN-120114412-A Curcumin-loaded nano delivery system and preparation method and application thereof 北京工商大学 2025-06-10 — — CN disclosed
CN-119868249-A Transdermal delivery formulation 阿尔伯特爱因斯坦医学院 2025-04-25 — — CN disclosed
CN-119192614-A Hydrogel for improving photocuring 3D printing precision and application thereof 福州大学 2024-12-27 — — CN disclosed
CN-119036834-A DLP photo-curing 3D printing system and printing method 广东工业大学 2024-11-29 — — CN disclosed
CN-116421584-B Curcumin ionic liquid medicine carrying film and preparation method and application thereof 东南大学 2024-03-12 — — CN disclosed
CN-116421584-B Curcumin ionic liquid medicine carrying film and preparation method and application thereof 东南大学 2024-03-12 — — CN disclosed
CN-117378706-A Feed additive for improving disease resistance of animals and application thereof 武汉轻工大学 2024-01-12 — — CN disclosed
CN-116983375-A Traditional Chinese medicine powder for treating newcastle disease and preparation method thereof 北京赛孚生物药业有限公司 2023-11-03 — — CN disclosed
CN-103385872-B Pharmaceutical composition of a kind of Hepatoma therapy and preparation method thereof GUIZHOU SHENQI DRUG RESEARCH INSTITUTE (CN) 2015-11-18 — — CN disclosed
CN-104206955-A Lycium ruthenicum tablet for reducing blood fat GOU CHUNHU 2014-12-17 — — CN disclosed
CN-103431377-A Foodstuff capable of reducing blood pressure and preventing complications GOU CHUNHU 2013-12-11 — — CN disclosed
CN-103393639-A Medicinal composition for treating lung cancer and preparation method thereof GUIZHOU SHENQI PHARMACEUTICAL RES INST 2013-11-20 — — CN disclosed
CN-103385872-A Pharmaceutical composition for treating liver cancer and preparation method thereof GUIZHOU SHENQI DRUG RES INST 2013-11-13 — — CN disclosed
CN-102697035-A Cordyceps anti-aging pellet CHUNHU GOU 2012-10-03 — — CN disclosed
CN-102657866-A Cancer prevention and fighting capsules CHUNHU GOU 2012-09-12 — — CN disclosed
US-20040202640-A1 Method for topical treatment of scars with rotein Kinase C inhibitors CRANDALL WILSON TRAFTON 2004-10-14 — — US disclosed
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