Slc-0111

Slc-0111

SCHEMBL672955

NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(F)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 16/20 1.00
CA2 P00918 16/20 1.00
CA9 Q16790 16/20 1.00
CA12 O43570 14/20 1.00
CA4 P22748 2/20 1.00
CA7 P43166 2/20 1.00
KMT2A Q03164 2/20 0.82
PTPN7 P35236 1/20 0.70
MEN1 O00255 1/20 0.70
MAPT P10636 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28499329 0.91 KMT2A (1.00) CA1CA2CA9CA12CA4
SCHEMBL672116 0.85 CA2 (1.00) CA1CA2CA9CA12CA4
SCHEMBL27468719 0.85 CA2 (0.84) CA1CA2CA9CA12CA4
SCHEMBL673008 0.85 CA1 (1.00) CA1CA2CA9CA12CA4
SCHEMBL672734 0.84 CA2 (1.00) CA1CA2CA9CA12CA4
SCHEMBL4554956 0.84 CA2 (0.74) CA1CA2CA9CA12CA4
SCHEMBL31310457 0.84 CA1 (1.00) CA1CA2CA9CA12CA4
SCHEMBL671546 0.84 CA2 (1.00) CA1CA2CA9CA12CA4
SCHEMBL15134184 0.84 KMT2A (0.85) CA1CA2CA9CA12CA4
SCHEMBL3070329 0.82 KMT2A (0.76) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4637846-A1 IMAGING REAGENTS AND METHODS Telix Pharmaceuticals (Innovations) Pty Ltd (AU) 2025-10-29 EP claimed
WO-2025065045-A1 NOVEL THERAPEUTIC TARGETS TELIX PHARMACEUTICALS (INNOVATIONS) PTY LTD (AU) 2025-04-03 WO claimed
WO-2024130293-A1 IMAGING REAGENTS AND METHODS TELIX PHARMACEUTICALS (INNOVATIONS) PTY LTD (AU) 2024-06-27 WO claimed
CN-109608371-B O2-4- (3- (4-sulfamoylphenyl) urea) phenylazoium dialkoxide derivative, preparation method and application 泰州学院 2020-12-29 CN claimed
CN-109608371-A O2-4- (3- (4-sulfamoylphenyl) urea) phenylazoium dialkoxide derivative, preparation method and application 泰州学院 2019-04-12 CN claimed
US-9962398-B2 Sulfonamide compounds for inhibition of metastatic tumor growth WELICHEM BIOTECH INC. (CA) 2018-05-08 US claimed
EP-2590938-B1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH WELICHEM BIOTECH INC (CA) 2017-06-07 EP claimed
US-20170007627-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH WELICHEM BIOTECH INC. (CA) 2017-01-12 US claimed
US-20130190396-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH METASIGNAL THERAPEUTICS INC. (CA) 2013-07-25 US claimed
EP-2590938-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH Metasignal Therapeutics Inc. (CA) 2013-05-15 EP claimed
WO-2012021963-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH METASIGNAL THERAPEUTICS INC. (CA) 2012-02-23 WO claimed
CN-117417465-B Hydroxyalkyl starch compound and preparation method and application thereof 华中科技大学 2026-02-27 CN disclosed
US-12522566-B2 2-(3-(2-methyl-6-(p-tolyl) pyridine-3-yl) ureido) benzenesulfonamide and derivatives as inhibitor of carbonic anhydrase IX for the treatment of cancer YEDITEPE UNIVERSITESI (TR) 2026-01-13 US disclosed
US-20260009799-A1 CA-IX TARGETING FLUORESCENT PROBES BRACCO IMAGING S.P.A. (IT) 2026-01-08 US disclosed
US-20250352675-A1 CA-IX TARGETING FLUORESCENT PROBES BRACCO IMAGING S.P.A. (IT) 2025-11-20 US disclosed
US-20130190396-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH METASIGNAL THERAPEUTICS INC. (CA) 2013-07-25 US disclosed
US-20130190396-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH METASIGNAL THERAPEUTICS INC. (CA) 2013-07-25 US disclosed
EP-2590938-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH Metasignal Therapeutics Inc. (CA) 2013-05-15 EP disclosed
WO-2012021963-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH METASIGNAL THERAPEUTICS INC. (CA) 2012-02-23 WO disclosed
WO-2012021963-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH METASIGNAL THERAPEUTICS INC. (CA) 2012-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130190396-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH HIF1AN, CBX2, HIF1A CA1 31/4885CA2 5/4885CA9 25/4885
US-20260009799-A1 CA-IX TARGETING FLUORESCENT PROBES CA9, CA12, CA1 CA1 3/4885CA2 6/4885CA9 1/4885
US-20170007627-A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH HIF1AN, CBX2, HIF1A CA1 31/4885CA2 5/4885CA9 25/4885
US-20250352675-A1 CA-IX TARGETING FLUORESCENT PROBES CA9, CA4, CA7 CA1 9/4885CA2 8/4885CA9 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.