SCHEMBL6729705

SCHEMBL6729705

C[C@@H]1CN(S(=O)(=O)c2cc3cc(Cl)ccc3n2S(=O)(=O)c2ccccc2)C[C@H](C)[N+]1(C(=O)c1ccc(Br)cc1)C(=O)c1ccc(Br)cc1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 0.43
PPARA Q07869 5/20 0.43
PPARD Q03181 5/20 0.43
ACLY P53396 12/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6730735 0.77 PPARG (0.47) PPARGPPARAPPARDACLY
SCHEMBL6730739 0.77 PPARG (0.47) PPARGPPARAPPARDACLY
SCHEMBL6424043 0.70 MAPT (0.52) PPARGPPARAPPARDACLY
SCHEMBL6733988 0.70 PPARG (0.44) PPARGPPARAPPARDACLY
SCHEMBL4938276 0.69 KMT2A (0.64)
SCHEMBL739191 0.69 PPARG (0.58) PPARGPPARAPPARDACLY
SCHEMBL6774913 0.69 PPARG (0.58) PPARGPPARAPPARDACLY
SCHEMBL6733146 0.69 PPARG (0.45) PPARGPPARAPPARDACLY
SCHEMBL6730443 0.69 PPARG (0.50) PPARGPPARAPPARD
SCHEMBL6725421 0.68 PPARG (0.43) PPARGPPARAPPARDACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 PPARG 1204/4885PPARA 573/4885PPARD 875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.