2-Picolinic Acid

2-Picolinic Acid

SCHEMBL672972

O=C(O)c1ccccn1.[Fe]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.95
L3MBTL1 Q9Y468 2/20 0.95
NAPRT Q6XQN6 1/20 0.95
P4HTM Q9NXG6 1/20 0.95
CES2 O00748 1/20 0.67
CES1 P23141 1/20 0.67
KMT2A Q03164 2/20 0.63
ALDH1A1 P00352 2/20 0.61
GSK3B P49841 1/20 0.55
KDM4E B2RXH2 4/20 0.54
MAPT P10636 2/20 0.54
KDM6B O15054 1/20 0.54
TET3 O43151 1/20 0.54
KDM4A O75164 1/20 0.54
BBOX1 O75936 1/20 0.54
KDM5A P29375 1/20 0.54
KDM5C P41229 1/20 0.54
ASPH Q12797 1/20 0.54
KDM4D Q6B0I6 1/20 0.54
TET2 Q6N021 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL2164674 0.98 LMNA (0.91) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL29368665 0.98
2-Picolinic Acid SCHEMBL28737810 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL674837 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL7457912 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL36055 0.98
2-Picolinic Acid SCHEMBL12537807 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL5058102 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL22835776 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL20721125 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12268676-B2 Antiviral applications of picolinic acid and its derivatives INDIAN INSTITUTE OF SCIENCE (IN) 2025-04-08 US claimed
CN-114685702-B Method for preparing poly-conjugated diene by using pyridine imine iron catalyst and application of poly-conjugated diene 中国科学院青岛生物能源与过程研究所 2023-08-18 CN claimed
CN-114874362-B Pyridinimine oxime iron catalyst, preparation method thereof and application thereof in conjugated diene polymerization 中国科学院青岛生物能源与过程研究所 2023-05-23 CN claimed
CN-112939854-B Iron hydroxypyridine carboxylic acid complex, synthesis method thereof and application of iron hydroxypyridine carboxylic acid complex in preparing carbon monoxide by photocatalytic reduction of carbon dioxide 云南师范大学 2022-12-06 CN claimed
WO-2022157656-A1 ANTIVIRAL APPLICATIONS OF PICOLINIC ACID AND ITS DERIVATIVES INDIAN INSTITUTE OF SCIENCE (IN) 2022-07-28 WO claimed
US-20220226292-A1 Antiviral Applications of Picolinic Acid and its Derivatives INDIAN INSTITUTE OF SCIENCE (IN) 2022-07-21 US claimed
CN-105813478-B Beverage containing ferrous picolinate 雀巢产品有限公司 2019-12-20 CN claimed
EP-3086666-B1 BEVERAGE COMPRISING FERROUS PICOLINATE NESTEC SA (CH) 2017-10-11 EP claimed
EP-3086665-B1 FOOD COMPOSITION COMPRISING FERROUS PICOLINATE NESTEC SA (CH) 2017-10-11 EP claimed
US-20160374370-A1 BEVERAGE COMPRISING FERROUS PICOLINATE NESTEC S.A. (CH) 2016-12-29 US claimed
EP-3086665-A1 FOOD COMPOSITION COMPRISING FERROUS PICOLINATE Nestec S.A. (CH) 2016-11-02 EP claimed
US-20160309764-A1 FOOD COMPOSITION COMPRISING FERROUS PICOLINATE Société des Produits Nestlé S.A. (CH) 2016-10-27 US claimed
WO-2015091093-A1 FOOD COMPOSITION COMPRISING FERROUS PICOLINATE NESTEC S.A. (CH) 2015-06-25 WO claimed
WO-2015091092-A1 BEVERAGE COMPRISING FERROUS PICOLINATE NESTEC S.A. (CH) 2015-06-25 WO claimed
EP-1411965-A4 METHODS AND COMPOSITIONS FOR CONTROLLING PROTEIN ASSEMBLY OR AGGREGATION NOVACTYL INC (US) 2006-01-11 EP claimed
EP-1411965-A1 METHODS AND COMPOSITIONS FOR CONTROLLING PROTEIN ASSEMBLY OR AGGREGATION Novactyl, Inc. (US) 2004-04-28 EP claimed
WO-2003006044-A1 METHODS AND COMPOSITIONS FOR CONTROLLING PROTEIN ASSEMBLY OR AGGREGATION NOVACTYL, INC. (US) 2003-01-23 WO claimed
US-20020037908-A1 Methods and compositions for controlling protein assembly or aggregation NOVACTYL, INC. 2002-03-28 US claimed
US-RE33988-E Dietary supplementation with essential metal picolinates The United States of America as repesented by the Secretary of Agriculture (US) 1992-07-07 US claimed
US-4315927-A Dietary supplementation with essential metal picolinates THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1982-02-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037908-A1 Methods and compositions for controlling protein assembly or aggregation PSEN1, PSEN2, PRNP LMNA 1073/4885L3MBTL1 4530/4885NAPRT 1920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.