Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | RARG | P13631 | 4/20 | 0.47 |
| ▸ | RARA | P10276 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.46 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.42 |
| ▸ | MDH1 | P40925 | 2/20 | 0.42 |
| ▸ | MDH2 | P40926 | 2/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6732835 | 0.92 | RARA (0.52) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL6734668 | 0.91 | RARA (0.57) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL8482688 | 0.85 | RARA (0.54) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL7770118 | 0.85 | RARA (0.43) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL7769650 | 0.84 | KMT2A (0.46) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL6736410 | 0.83 | RARA (0.62) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL566278 | 0.83 | RARA (0.62) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL7769595 | 0.81 | RARA (0.42) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL7771740 | 0.79 | RARA (0.44) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL7770213 | 0.78 | RARA (0.47) | RARBRARGRARAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162339-A1 | Heterocyclic biaryl compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | DIAZ PHILIPPE (FR) | 2004-08-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162339-A1 | Heterocyclic biaryl compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | TYR, MITF, CYP1B1 | RARB 619/4885RARG 576/4885RARA 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.