Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729973 | 1.00 | TTR (0.58) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL5211560 | 0.92 | TTR (0.56) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL5211559 | 0.92 | TTR (0.56) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL27915164 | 0.90 | CA12 (0.67) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL20269220 | 0.89 | APP (0.60) | TTRPTGS2CYP3A4AKR1B10AKR1B1 | |
| SCHEMBL20269219 | 0.89 | APP (0.60) | TTRPTGS2CYP3A4AKR1B10AKR1B1 | |
| SCHEMBL27520645 | 0.88 | TTR (0.52) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL27520643 | 0.88 | TTR (0.52) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4427604 | 0.88 | TTR (0.69) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4427602 | 0.88 | TTR (0.69) | TTRDPP4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110876278-A | Magnetic shielding sheet with fragrance and preparation method and application thereof | 江苏金羿先磁新材料科技有限公司 | 2020-03-10 | — | — | CN | claimed |
| US-6677465-B2 | DIHYDROXYLATION OF 3-PHENYL CINNAMATE BY OSMIUM (VIII) OXIDE CATALYSIS IN PRESENCE OF SHARPLESS LIGAND AND OXIDIZING AGENT, SELECTIVE CONVERSION OF HYDROXY IN 2 POSITION TO LEAVING GROUP, INTRAMOLECULAR SUBSTITUTION TO FORM GLYCIDE ESTER | ABBOTT GMBH & CO. KG (DE) | 2004-01-13 | — | — | US | disclosed |
| US-20030162982-A1 | Method for the enantioselective preparation of 3,3-diphenyl-2,3-epoxy propionic acid esters | ROYALTY PHARMA COLLECTION TRUST | 2003-08-28 | — | — | US | disclosed |
| US-5627189-A | Insecticidal 5-substituted-2,4-diaminopyrimidine derivatives | FMC CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| US-5587379-A | CONTROLLING INSECTS IN AGRICULTURAL CROPS | FMC CORPORATION (US) | 1996-12-24 | — | — | US | disclosed |
| US-5521192-A | TOBACCO BUDWORM, CABBAGE LOOPER, BEET ARMYWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0671881-A4 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES. | FMC CORP (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0671881-A1 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES | FMC CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012032-A1 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES | FMC CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162982-A1 | Method for the enantioselective preparation of 3,3-diphenyl-2,3-epoxy propionic acid esters | ALDH3A1, HAO2, ERGIC1 | TTR 3890/4885DPP4 678/4885CA12 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.