⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252839 | 1.00 | TSHR (0.37) | — | |
| SCHEMBL28630734 | 0.88 | — | — | |
| SCHEMBL27316114 | 0.87 | MGLL (0.33) | — | |
| SCHEMBL27297736 | 0.86 | SLC29A1 (0.36) | — | |
| SCHEMBL27807728 | 0.82 | — | — | |
| SCHEMBL9556920 | 0.82 | — | — | |
| SCHEMBL19313452 | 0.82 | KDM4E (0.46) | — | |
| Ammonia Solution, Strong SCHEMBL27450984 | 0.80 | ALDH1A1 (0.45) | — | |
| SCHEMBL5222819 | 0.71 | HRH3 (0.32) | — | |
| SCHEMBL10603635 | 0.70 | POLB (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102337298-A | Immune nano-carrier for conveying siRNA (small interfering Ribonucleic Acid) and preparation method and application thereof | KAIHONG HUANG | 2012-02-01 | — | — | CN | claimed |
| CN-102329810-A | siRNA conveying carrier and application thereof | KAIHONG HUANG | 2012-01-25 | — | — | CN | claimed |
| US-20110171144-A1 | Functional Micelles for Hard Tissue Targeted Delivery of Chemicals | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2011-07-14 | — | — | US | claimed |
| CN-101721709-A | Calcium phosphate and amphiphilic polymer composite medicament-carrying nano-microsphere, preparation method and application | SHANGHAI PESTICIDE RES INST | 2010-06-09 | — | — | CN | claimed |
| CN-101284133-A | Drug carried target cationic polymer for injections and modified by integrin ligand | SHANGHAI CANCER INST (CN) | 2008-10-15 | — | — | CN | claimed |
| EP-4299133-A2 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | VIIV Healthcare Company (US) | 2024-01-03 | — | — | EP | disclosed |
| WO-2023118447-A1 | NEW EGFRVIII-BINDING PEPTIDES, CONJUGATES AND USES THEREOF | NANOTHERA BIOSCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| US-11530296-B2 | Cationic polymers with D-fructose substituents | FRIEDRICH-SCHILLER-UNIVERSITAET JENA (DE) | 2022-12-20 | — | — | US | disclosed |
| CN-115386033-A | Binder for lithium ion battery and lithium ion battery using same | 深圳市动力源泉电子有限公司 | 2022-11-25 | — | — | CN | disclosed |
| US-20220211714-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2022-07-07 | — | — | US | disclosed |
| US-11311545-B2 | Compositions and methods for the delivery of therapeutics | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2022-04-26 | — | — | US | disclosed |
| US-20220110882-A1 | SYNTHETICALLY LETHAL NANOPARTICLES FOR TREATMENT OF CANCERS | UNIV IOWA RES FOUND (US) | 2022-04-14 | — | — | US | disclosed |
| US-6221959-B1 | POLYNUCLEOTIDE, POLYMER COMPLEX | SUPRATEK PHARMA, INC. (CA) | 2001-04-24 | — | — | US | disclosed |
| WO-2000047186-A1 | POLYNUCLEOTIDE COMPOSITIONS FOR INTRAMUSCULAR AND INTRADERMAL ADMINISTRATION | SUPRATEK PHARMA INC. (CA) | 2000-08-17 | — | — | WO | disclosed |
| EP-1003527-A1 | POLYNUCLEOTIDE COMPOSITIONS | SUPRATEK PHARMA, INC. (CA) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999006055-A1 | POLYNUCLEOTIDE COMPOSITIONS | SUPRATEK PHARMA INC. (CA) | 1999-02-11 | — | — | WO | disclosed |
| EP-0236987-B1 | Chemically modified protein and production thereof | HOFFMANN LA ROCHE (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-5109120-A | REDUCTION OF CHEMICALLY MODIFIED PROTEINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-28 | — | — | US | disclosed |
| EP-0236987-A2 | Chemically modified protein and production thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1987-09-16 | — | — | EP | disclosed |
| US-4391721-A | Dispersant viscosity index improver comprising reaction product of a styrene-maleic anhydride copolymer, an aliphatic alcohol and a tertiary amino alcohol | STANDARD OIL COMPANY (INDIANA) (US) | 1983-07-05 | — | — | US | disclosed |