SCHEMBL6730859

SCHEMBL6730859

CCC(OC)C1CC(C)(C)N(C)C(C)(C)C1(N)c1nc(Cl)nc(C2(N)C(C(CC)OC)CC(C)(C)N(C)C2(C)C)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909763 0.61
SCHEMBL714017 0.57 GAA (0.36)
SCHEMBL698651 0.57 IDH1 (0.33)
SCHEMBL8838294 0.54 PDE10A (0.31)
SCHEMBL8715510 0.54 SGK1 (0.32)
SCHEMBL5645604 0.54
SCHEMBL8459826 0.53 LMNA (0.37)
SCHEMBL21385325 0.52 PDE10A (0.30)
SCHEMBL8838244 0.51 LMNA (0.42)
SCHEMBL10802588 0.51 PDE4A (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040192877-A1 Property enhancement of polyamides by co-condensation with lightstabilizers CLARIANT FINANCE (BVI) LIMITED (VG) 2004-09-30 US disclosed
EP-1423464-A1 PROPERTY ENHANCEMENT OF POLYAMIDES BY CO-CONDENSATION WITH LIGHTSTABILIZERS Clariant Finance (BVI) Limited (VG) 2004-06-02 EP disclosed
EP-1332176-A1 SYNERGISTIC STABILIZER COMPOSITIONS FOR COLOR STABLE PIGMENTED THERMOPLASTIC POLYMERS IN PROLONGED CONTACT WITH WATER Clariant Finance (BVI) Limited (VG) 2003-08-06 EP disclosed
WO-2003014215-A1 PROPERTY ENHANCEMENT OF POLYAMIDES BY CO-CONDENSATION WITH LIGHTSTABILIZERS CLARIANT INTERNATIONAL LTD (CH) 2003-02-20 WO disclosed
WO-2002012385-A1 SYNERGISTIC STABILIZER COMPOSITIONS FOR COLOR STABLE PIGMENTED THERMOPLASTIC POLYMERS IN PROLONGED CONTACT WITH WATER CLARIANT FINANCE (BVI) LIMITED (VG) 2002-02-14 WO disclosed