SCHEMBL714017

SCHEMBL714017

CCCC(Nc1nc(Cl)nc(NC(CCC)C2CC(C)(C)N(C)C(C)(C)C2)n1)C1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
IDH1 O75874 1/20 0.35
IDH2 P48735 1/20 0.35
LMNA P02545 1/20 0.33
SOS1 Q07889 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698651 0.97 IDH1 (0.33) GAATDP1IDH1IDH2SOS1
SCHEMBL3145310 0.90 KMT2A (0.36) GAATDP1IDH1IDH2
SCHEMBL8838291 0.87 FLT3 (0.31) IDH1IDH2
SCHEMBL7458937 0.86 IDH1 (0.33) GAATDP1IDH1IDH2LMNA
SCHEMBL7990249 0.84 IDH1 (0.31) GAATDP1IDH1IDH2
SCHEMBL9373097 0.84 FLT3 (0.39)
SCHEMBL711948 0.83 GAA (0.37) GAATDP1IDH1IDH2LMNA
SCHEMBL20608531 0.83 GAA (0.33) GAATDP1IDH1IDH2
SCHEMBL692773 0.82 ALDH1A1 (0.31) IDH1IDH2
SCHEMBL7456205 0.81 KMT2A (0.35) IDH1IDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112239458-A Hindered amine light stabilizer intermediate and preparation method of hindered amine light stabilizer 利安隆(天津)新材料科技有限公司 2021-01-19 CN disclosed
US-9963575-B2 Sterically hindered amine light stabilizers with a mixed functionalization BASF SE (DE) 2018-05-08 US disclosed
US-20170107352-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION BASF SE (DE) 2017-04-20 US disclosed
US-9550941-B2 Sterically hindered amine light stabilizers with a mixed functionalization BASF SE (DE) 2017-01-24 US disclosed
EP-2630137-B1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH MIXED FUNCTIONALIZATION BASF SE (DE) 2015-04-01 EP disclosed
US-8830811-B2 Resin composition and optical component MITSUI CHEMICALS, INC. (JP) 2014-09-09 US disclosed
EP-2630137-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH MIXED FUNCTIONALIZATION BASF SE (DE) 2013-08-28 EP disclosed
US-20130207043-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION BASF SE (DE) 2013-08-15 US disclosed
EP-1878769-B1 RESIN COMPOSITION AND OPTICAL COMPONENT MITSUI CHEMICALS INC (JP) 2013-04-17 EP disclosed
US-8354529-B2 Polyamine derivative and polyol derivative BASF SE (DE) 2013-01-15 US disclosed
EP-0319480-B1 Process for the methylation of triazine compounds containing 2,2,6,6-tetramethylpiperidine groups CIBA GEIGY AG (CH) 1994-01-26 EP disclosed
US-5268401-A Steric hindered 2,2,6,6-tetramethylpiperidine ring CIBA-GEIGY CORPORATION (US) 1993-12-07 US disclosed
EP-0427672-B1 POLYMER STABILIZERS CONTAINING BOTH HINDERED AMINE AND HYDROXYLAMINE MOIETIES CIBA-GEIGY AG (CH) 1993-09-29 EP disclosed
US-5202441-A Heat resistance, photostability CIBA-GEIGY CORPORATION (US) 1993-04-13 US disclosed
US-5134233-A Light stabilizers for organic materials CIBA-GEIGY CORPORATION (US) 1992-07-28 US disclosed
US-5130429-A Methylation with formaldehyde in a solvent and distillation CIBA-GEIGY CORPORATION (US) 1992-07-14 US disclosed
EP-0461071-A1 Piperidine-triazine compounds containing silane groups, for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1991-12-11 EP disclosed
EP-0455588-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1991-11-06 EP disclosed
EP-0427672-A1 Polymer stabilizers containing both hindered amine and hydroxylamine moieties CIBA-GEIGY AG (CH) 1991-05-15 EP disclosed
EP-0319480-A2 Process for the methylation of triazine compounds containing 2,2,6,6-tetramethylpiperidine groups CIBA-GEIGY AG (CH) 1989-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130207043-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION C1S, H1-0, H1-2 GAA 4492/4885TDP1 4246/4885IDH1 3394/4885
US-20170107352-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION C1S, H1-0, H1-2 GAA 4426/4885TDP1 4146/4885IDH1 3469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.