Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 5/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20524969 | 0.84 | MAPK1 (0.45) | MAPTSRD5A2PDE5AKDM1AMAOB | |
| SCHEMBL20524971 | 0.84 | MAPK1 (0.45) | MAPTSRD5A2PDE5AKDM1AMAOB | |
| SCHEMBL5837836 | 0.81 | SLC6A2 (0.52) | SLC6A2SLC6A4PDE4BKCNQ3KCNQ2 | |
| SCHEMBL5837839 | 0.81 | SLC6A2 (0.52) | SLC6A2SLC6A4PDE4BKCNQ3KCNQ2 | |
| SCHEMBL5837841 | 0.81 | SLC6A2 (0.52) | SLC6A2SLC6A4PDE4BKCNQ3KCNQ2 | |
| SCHEMBL6735711 | 0.81 | SLC6A2 (0.47) | SLC6A2SLC6A4PDE4BKMT2AMAPT | |
| SCHEMBL5838942 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4PDE4BKCNQ3KCNQ2 | |
| SCHEMBL28391452 | 0.81 | SLC6A2 (0.51) | SLC6A2SLC6A4PDE4BKCNQ3KCNQ2 | |
| SCHEMBL5838306 | 0.78 | SLC6A2 (0.49) | SLC6A2SLC6A4PDE4B | |
| SCHEMBL28390568 | 0.78 | MAPT (0.51) | SLC6A2SLC6A4KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | CYP46A1, REN, CYP11B2 | SLC6A2 1559/4885SLC6A4 3069/4885PDE4B 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.