Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998883 | 0.82 | ALDH1A1 (0.63) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL12655929 | 0.78 | TOP1 (0.56) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL8619827 | 0.77 | APP (0.50) | MAPTALDH1A1TDP1THRBNPC1 | |
| SCHEMBL6541802 | 0.76 | ALOX15 (0.57) | MEN1KMT2AMAPTALDH1A1PELI1 | |
| SCHEMBL16076897 | 0.75 | TSHR (0.56) | MEN1KMT2AMAPTALDH1A1PELI1 | |
| SCHEMBL6642887 | 0.74 | TDP1 (0.51) | MEN1KMT2AMAPTALDH1A1PELI1 | |
| SCHEMBL6738366 | 0.74 | TSHR (0.76) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL4667734 | 0.74 | ALDH1A1 (0.63) | MEN1KMT2AMAPTALDH1A1PELI1 | |
| SCHEMBL8755737 | 0.73 | NPC1 (0.63) | MAPTALDH1A1TDP1THRBNPC1 | |
| SCHEMBL27544531 | 0.73 | MAPT (0.57) | MEN1KMT2AMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110757-A1 | Flt-1 ligands and their uses in the treatment of diseases regulatable by angiogenesis | ARRHENIUS THOMAS (US) | 2004-06-10 | — | — | US | disclosed |
| EP-1370250-A2 | FLT-1 LIGANDS AND THEIR USES IN THE TREATMENT OF DISEASES REGULATABLE BY ANGIOGENESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002076438-A2 | FLT-1 LIGANDS AND THEIR USES IN THE TREATMENT OF DISEASES REGULATABLE BY ANGIOGENESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110757-A1 | Flt-1 ligands and their uses in the treatment of diseases regulatable by angiogenesis | FLT1, FLT4, TEK | MEN1 1965/4885KMT2A 2223/4885MAPT 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.