Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6735869 | 0.86 | ESR1 (0.51) | ESR1ESR2MIFLY96TSHR | |
| SCHEMBL6738744 | 0.86 | ESR1 (0.43) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL6738748 | 0.85 | ESR1 (0.40) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL6738478 | 0.84 | PPARG (0.51) | — | |
| SCHEMBL6736991 | 0.83 | SLC7A5 (0.45) | ESR1ESR2SLC7A5BLM | |
| SCHEMBL3533617 | 0.76 | PPARA (0.50) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL3533612 | 0.76 | PPARA (0.50) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL6736319 | 0.74 | ESR1 (0.46) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL12755046 | 0.74 | ATM (0.44) | CA12CA2CA7CA9CA14 | |
| SCHEMBL11202582 | 0.74 | SRR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248849-A1 | 3-Aryl-A-oxy substituted propanoic acids and a process for their preparation | DR. REDDY'S LABORATORIES INC. | 2004-12-09 | — | — | US | claimed |
| WO-2003002575-A1 | 3-ARYL-$G(a)-OXY SUBSTITUTED PROPANOIC ACIDS AND A PROCESS FOR THEIR PREPARATION | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-01-09 | — | — | WO | claimed |
| US-20040248849-A1 | 3-Aryl-A-oxy substituted propanoic acids and a process for their preparation | DR. REDDY'S LABORATORIES INC. | 2004-12-09 | — | — | US | disclosed |
| WO-2003002575-A1 | 3-ARYL-$G(a)-OXY SUBSTITUTED PROPANOIC ACIDS AND A PROCESS FOR THEIR PREPARATION | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248849-A1 | 3-Aryl-A-oxy substituted propanoic acids and a process for their preparation | GPR119, GLP1R, SLC5A1 | ESR1 3084/4885ESR2 1585/4885CA12 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.