Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4200916 | 0.88 | LTA4H (0.57) | LTA4HMAPTMEN1KMT2APABPC1 | |
| SCHEMBL22792637 | 0.84 | LTA4H (0.61) | LTA4HMAPTMEN1KMT2APABPC1 | |
| SCHEMBL5268459 | 0.84 | HIF1A (0.46) | LTA4HMAPTMEN1KMT2APABPC1 | |
| SCHEMBL4187374 | 0.82 | FYN (0.67) | LTA4HMAPTMEN1KMT2APABPC1 | |
| SCHEMBL6730573 | 0.82 | LTA4H (0.72) | LTA4HMAPTMEN1KMT2APABPC1 | |
| SCHEMBL5605047 | 0.81 | LTA4H (0.82) | LTA4HMAPTMEN1KMT2APABPC1 | |
| SCHEMBL11510145 | 0.81 | HIF1A (0.64) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11115803 | 0.81 | ALDH1A1 (0.69) | LTA4HMAPTMEN1KMT2APABPC1 | |
| SCHEMBL13766316 | 0.81 | LTA4H (0.66) | LTA4HMAPTMEN1KMT2APABPC1 | |
| SCHEMBL6733048 | 0.81 | LTA4H (0.66) | LTA4HMAPTMEN1KMT2APABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016102969-A1 | INHIBITION OF HAIR GROWTH | THE UNIVERSITY OF MANCHESTER (GB) | 2016-06-30 | — | — | WO | claimed |
| WO-2016102969-A1 | INHIBITION OF HAIR GROWTH | THE UNIVERSITY OF MANCHESTER (GB) | 2016-06-30 | — | — | WO | disclosed |
| US-6800651-B2 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-10-05 | — | — | US | disclosed |
| US-20040006114-A1 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-01-08 | — | — | US | disclosed |
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006114-A1 | Potentiators of glutamate receptors | GRM1, GRIN1, GRM2 | LTA4H 1721/4885MAPT 3885/4885MEN1 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.