Allocryptopine

Allocryptopine

SCHEMBL673252

COc1ccc2c(c1OC)CN(C)CCc1cc3c(cc1C(=O)C2)OCO3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 7/20 1.00
KMT2A Q03164 3/20 1.00
CYP2C19 P33261 5/20 0.69
CYP3A4 P08684 5/20 0.69
KDM4E B2RXH2 3/20 0.69
TSHR P16473 2/20 0.69
MEN1 O00255 2/20 0.69
ALDH1A1 P00352 1/20 0.62
CYP1A2 P05177 3/20 0.55
LMNA P02545 2/20 0.53
DRD2 P14416 2/20 0.53
DRD1 P21728 2/20 0.53
F3 P13726 2/20 0.53
DRD4 P21917 1/20 0.53
DRD5 P21918 1/20 0.53
ADRA1A P35348 1/20 0.53
DRD3 P35462 1/20 0.53
BCHE P06276 1/20 0.52
CYP2C9 P11712 2/20 0.47
THPO P40225 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allocryptopine SCHEMBL29568468 1.00 CYP2D6 (1.00) CYP2D6KMT2ACYP2C19CYP3A4KDM4E
Allocryptopine SCHEMBL30477770 1.00 CYP2D6 (1.00) CYP2D6KMT2ACYP2C19CYP3A4KDM4E
SCHEMBL3368057 0.89 CYP2D6 (0.80) CYP2D6KMT2ACYP2C19CYP3A4KDM4E
SCHEMBL11891038 0.87 CYP2D6 (0.77) CYP2D6KMT2ACYP2C19CYP3A4KDM4E
SCHEMBL31501083 0.87 CYP2D6 (0.77) CYP2D6KMT2ACYP2C19CYP3A4KDM4E
SCHEMBL3271155 0.87 CYP2D6 (0.77) CYP2D6KMT2ACYP2C19CYP3A4KDM4E
SCHEMBL11817332 0.85 CYP2D6 (0.73) CYP2D6KMT2ACYP2C19CYP3A4KDM4E
SCHEMBL16970984 0.83 CYP2D6 (0.84) CYP2D6KMT2ACYP2C19CYP3A4KDM4E
Allocryptopine SCHEMBL10384490 0.82 CYP2D6 (0.67) CYP2D6KMT2ACYP2C19CYP3A4KDM4E
SCHEMBL178013 0.82 CYP2D6 (1.00) CYP2D6KMT2ACYP2C19CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687856-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS Therapeutics, LLC (US) 2026-02-11 EP claimed
US-12485112-B2 Pharmaceutical composition ASCLEPIUS PHARMACEUTICAL LLC (US) 2025-12-02 US claimed
CN-119432631-A Recombinant bacterium and application thereof in production of benzophenanthridine alkaloids 陈云 2025-02-14 CN claimed
WO-2024229159-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC (US) 2024-11-07 WO claimed
US-20240366525-A1 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC 2024-11-07 US claimed
CN-118806779-A Pharmaceutical composition and preparation method and application thereof 陕西盘龙药业集团股份有限公司 2024-10-22 CN claimed
CN-118518778-A Detection method and screening method for quality markers of artemisia rupestris 西南民族大学 2024-08-20 CN claimed
US-20240148705-A1 PHARMACEUTICAL COMPOSITION ASCLEPIUS PHARMACEUTICAL LLC (US) 2024-05-09 US claimed
US-11865107-B2 Pharmaceutical composition ASCLEPIUS PHARMACEUTICAL LLC (US) 2024-01-09 US claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
JP-2006516633-A 2006-07-06 JP claimed
WO-2006032380-A1 QUATERNARY ALKALOID DERIVATIVES OF CHELIDONIUM MAJUS L NOWICKY WASSILI (AT) 2006-03-30 WO claimed
CN-1747726-A A therapeutic composition for the treatment of hiv-1 and hiv-2 EXCYTON EXCYMER GMBH (CH) 2006-03-15 CN claimed
EP-1589961-A4 A THERAPEUTIC COMPOSITION FOR THE TREATMENT OF HIV-1 AND HIV-2 EXCYTON EXCYMER GMBH (CH) 2006-02-15 EP claimed
EP-1589961-A2 A THERAPEUTIC COMPOSITION FOR THE TREATMENT OF HIV-1 AND HIV-2 Excyton-Excymer GmbH (CH) 2005-11-02 EP claimed
CN-1218948-C Process for separating and preparing hig purity samguinarine and chelerythrine UNIV HUNAN NORMAL (CN) 2005-09-14 CN claimed
CN-1532198-A Quaternary chelidonine derivatives ά����ŵά�Ļ� 2004-09-29 CN claimed
CN-1532197-A Process for separating and preparing hig purity samguinarine and chelerythrine 湖南师范大学 2004-09-29 CN claimed
WO-2004066954-A2 A THERAPEUTIC COMPOSITION FOR THE TREATMENT OF HIV-1 AND HIV-2 EXCYTON-EXCYMER GMBH (CH) 2004-08-12 WO claimed
CN-1422859-A reaction method of alkaloid, reaction product and application thereof HUATZ NORVICH (AT) 2003-06-11 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12485112-B2 Pharmaceutical composition H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADRA2C, CPT1A CYP2D6 111/4885KMT2A 2630/4885CYP2C19 250/4885
US-20240148705-A1 PHARMACEUTICAL COMPOSITION H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADRA2C, CPT1A CYP2D6 111/4885KMT2A 2630/4885CYP2C19 250/4885
US-11865107-B2 Pharmaceutical composition H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADRA2C, CPT1A CYP2D6 111/4885KMT2A 2630/4885CYP2C19 250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.