SCHEMBL178013

SCHEMBL178013

CN1CCc2cc3c(cc2C(=O)Cc2ccc4c(c2C1)OCO4)OCO3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 8/20 1.00
CYP2C19 P33261 5/20 1.00
CYP3A4 P08684 4/20 1.00
TSHR P16473 3/20 1.00
KDM4E B2RXH2 2/20 1.00
KMT2A Q03164 2/20 0.79
MEN1 O00255 1/20 0.79
XBP1 P17861 1/20 0.49
CYP1A2 P05177 3/20 0.48
DRD1 P21728 1/20 0.46
DRD5 P21918 1/20 0.46
CYP2C9 P11712 3/20 0.43
LMNA P02545 1/20 0.43
HIF1A Q16665 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356135 1.00 CYP2D6 (1.00) CYP2D6CYP2C19CYP3A4TSHRKDM4E
Hydrochloric Acid SCHEMBL4456077 0.99 CYP2D6 (0.98) CYP2D6CYP2C19CYP3A4TSHRKDM4E
Hydrochloric Acid SCHEMBL29389905 0.99 CYP2D6 (0.98) CYP2D6CYP2C19CYP3A4TSHRKDM4E
Nitric Acid SCHEMBL3871762 0.93 CYP2D6 (0.86) CYP2D6CYP2C19CYP3A4TSHRKDM4E
SCHEMBL178039 0.88 KMT2A (1.00) CYP2D6CYP2C19CYP3A4TSHRKDM4E
SCHEMBL29419477 0.88 KMT2A (1.00) CYP2D6CYP2C19CYP3A4TSHRKDM4E
Stylopine SCHEMBL23524621 0.88 CYP2D6 (0.77) CYP2D6CYP2C19CYP3A4TSHRKDM4E
SCHEMBL9882661 0.83 CYP2D6 (0.71) CYP2D6CYP2C19CYP3A4TSHRKDM4E
Protopine SCHEMBL29613725 0.83 CYP2D6 (1.00) CYP2D6CYP2C19CYP3A4TSHRKDM4E
Allocryptopine SCHEMBL673252 0.82 CYP2D6 (1.00) CYP2D6CYP2C19CYP3A4TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1891 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714440-A2 A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS Kurek, Janusz (PL) 2026-03-25 EP claimed
EP-4687856-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS Therapeutics, LLC (US) 2026-02-11 EP claimed
US-12485112-B2 Pharmaceutical composition ASCLEPIUS PHARMACEUTICAL LLC (US) 2025-12-02 US claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
CN-120121741-A Detection method of traditional Chinese medicine composition 江苏康缘药业股份有限公司 2025-06-10 CN claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
CN-119955611-A Fermentation system and fermentation method capable of industrially producing active proto-type Conpu tea 贵州康普茶天然发酵饮料科技有限公司 2025-05-09 CN claimed
CN-119291083-B Quality control method of jindan accessory delay particles 江西省药品检验检测研究院 2025-05-02 CN claimed
CN-119901843-A Fingerprint construction method of nodules of breast resolving capsules/particles and fingerprint thereof 陕西白鹿制药股份有限公司 2025-04-29 CN claimed
CN-119745869-A Application of Dong medicine blood herb active ingredient protopine in anti-atherosclerosis medicine 南华大学 2025-04-04 CN claimed
CN-1429611-A Greater celandine extract and its preparation method and application ZHANG PING (CN) 2003-07-16 CN claimed
CN-1422859-A reaction method of alkaloid, reaction product and application thereof HUATZ NORVICH (AT) 2003-06-11 CN claimed
CN-1385157-A Application of protopine in preparing medicine for treating senile dementia KUNMING INST OF ANIMALS CHINES (CN) 2002-12-18 CN claimed
US-20010008641-A1 NUTRITIONALLY ACTIVE COMPOSITION FOR BODYBUILDING ADAMS FOODS, LTD. 2001-07-19 US claimed
CN-1280825-A Sigma-receptor acting medicine containing protopine-type alkaloid CHENGDU INST BIOLOGY CAS (CN) 2001-01-24 CN claimed
WO-2000003679-A2 NUTRITIONALLY ACTIVE COMPOSITION FOR HARDENING FINGERNAILS ADAMS FOOD LTD. (US) 2000-01-27 WO claimed
WO-1999061038-A1 COMPOSITION HAVING THERAPEUTIC AND/OR NUTRITIONALLY ACTIVE SUBSTITUENT ADAMS FOOD LTD. (US) 1999-12-02 WO claimed
US-4769452-A Production of purity benzo-c-phenanthridine alkaloid salts VIPONT LABORATORIES, INC. (US) 1988-09-06 US claimed
US-4683133-A PUMPING ALKALOID SALT SOLUTIONS ON GUMS VIPONT LABORATORIES, INC. (US) 1987-07-28 US claimed
US-4590061-A BENZO-C-PHENANTHRIDINE ALKALOIDS VIPONT LABORATORIES, INC. (US) 1986-05-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12485112-B2 Pharmaceutical composition H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADRA2C, CPT1A CYP2D6 111/4885CYP2C19 250/4885CYP3A4 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.