SCHEMBL673300

SCHEMBL673300

C=CC(=O)OCC[Si](C)(C)OCC

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.52
HPGD P15428 1/20 0.52
ALDH1A1 P00352 5/20 0.47
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
CYP3A4 P08684 2/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 3/20 0.44
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ATM Q13315 1/20 0.33
HCAR2 Q8TDS4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107693 0.90 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16536923 0.88 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16286804 0.87 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL29965163 0.87 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL29947959 0.87 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16537305 0.87 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1066175 0.86 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL270021 0.84 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16536863 0.83 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL18221800 0.83 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053528-B2 Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-11-08 US claimed
EP-2164902-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM Georgia-Pacific Chemicals LLC (US) 2010-03-24 EP claimed
US-20090124151-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-05-14 US claimed
WO-2008150647-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS, LLC (US) 2008-12-11 WO claimed
US-20240018358-A1 POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF KANEKA CORPORATION (JP) 2024-01-18 US disclosed
CN-117136204-A Polysiloxane resin and use thereof 株式会社钟化 2023-11-28 CN disclosed
WO-2023119928-A1 METHOD FOR PRODUCING DISPERSION LIQUID OR SOLUTION IN WHICH WATER CONTAINING POLYSILOXANE-BASED RESIN SERVES AS MEDIUM 株式会社カネカ 2023-06-29 WO disclosed
CN-111533854-B Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2023-03-31 CN disclosed
WO-2022202269-A1 POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF 株式会社カネカ 2022-09-29 WO disclosed
CN-109803826-B Laminate and method for producing same 信越化学工业株式会社 2021-05-11 CN disclosed
CN-108472685-B Method for producing laminate 信越化学工业株式会社 2021-02-02 CN disclosed
CN-111533854-A Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2020-08-14 CN disclosed
US-20160208132-A1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-07-21 US disclosed
EP-3045506-A1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE Shin-Etsu Chemical Co., Ltd. (JP) 2016-07-20 EP disclosed
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed
US-8053528-B2 Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-11-08 US disclosed
EP-2164902-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM Georgia-Pacific Chemicals LLC (US) 2010-03-24 EP disclosed
US-20090124151-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-05-14 US disclosed
WO-2008150647-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS, LLC (US) 2008-12-11 WO disclosed