SCHEMBL6733075

SCHEMBL6733075

Nc1cncc([N+](=O)[O-])c1N

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
MAPT P10636 4/20 0.42
TDP1 Q9NUW8 5/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
POLB P06746 1/20 0.41
ALOX15 P16050 1/20 0.41
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
GPR35 Q9HC97 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4457346 0.89 MAPT (0.50) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL8565256 0.81 MAPT (0.41) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL541960 0.79 ALDH1A1 (0.44) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL12515483 0.79 MEN1 (0.41) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL16787435 0.79 ALDH1A1 (0.46) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL16026726 0.79 TSHR (0.44) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL1958391 0.79 ALDH1A1 (0.53) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL13482304 0.79 MAPT (0.40) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL30811745 0.76 PTPN11 (0.44) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL2219710 0.75 ALDH1A1 (0.48) ALDH1A1MAPTTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114686031-B Corrosion-resistant fluorescent paint and preparation method thereof 森固(山东)新材料有限公司 2023-04-14 CN claimed
CN-115772357-A Preparation method of corrosion-resistant fluorescent paint 张国伟 2023-03-10 CN claimed
CN-114686031-A Corrosion-resistant fluorescent paint and preparation method thereof 张国伟 2022-07-01 CN claimed
CN-114686031-B Corrosion-resistant fluorescent paint and preparation method thereof 森固(山东)新材料有限公司 2023-04-14 CN disclosed
CN-114686031-B Corrosion-resistant fluorescent paint and preparation method thereof 森固(山东)新材料有限公司 2023-04-14 CN disclosed
CN-115772357-A Preparation method of corrosion-resistant fluorescent paint 张国伟 2023-03-10 CN disclosed
CN-115772357-A Preparation method of corrosion-resistant fluorescent paint 张国伟 2023-03-10 CN disclosed
CN-114686031-A Corrosion-resistant fluorescent paint and preparation method thereof 张国伟 2022-07-01 CN disclosed
CN-114686031-A Corrosion-resistant fluorescent paint and preparation method thereof 张国伟 2022-07-01 CN disclosed
WO-2021121420-A1 BENZOPYRAZOLE COMPOUND AND INTERMEDIATE, PREPARATION METHOD, AND APPLICATION THEREOF 江苏凯迪恩医药科技有限公司 2021-06-24 WO disclosed
WO-2017168333-A1 AMIFAMPRIDINE DIHYDROCHLORIDE SHILPA MEDICARE LIMITED (IN) 2017-10-05 WO disclosed
WO-2001007045-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2001-02-01 WO disclosed
WO-2000001697-A1 IMIDAZO-PYRIDINES, -PYRIDAZINES, AND -TRIAZINES AS CORTICOTROPIN RELEASING FACTOR ANTAGONISTS DU PONT PHARMACEUTICALS COMPANY (US) 2000-01-13 WO disclosed
EP-0255217-B1 FUSED IMIDAZOHETEROCYCLIC COMPOUNDS A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) 1992-01-22 EP disclosed
US-4948800-A MUSCLE RELAXANTS; ANTICONVULSANTS; ANXIOLYTIC AGENTS; 3-HYDROXYALKYL-PYRIDO(4,5-B OR-C)IMIDAZOLE COMPOUNDS A. H. ROBINS COMPANY, INCORPORATED (US) 1990-08-14 US disclosed
US-4914109-A ANTICONVULSANTS, ANTIANXIETY AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1990-04-03 US disclosed
US-4873251-A MUSCLE RELAXANTS, ANTICONVULSANTS, ANTIANXIETY AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1989-10-10 US disclosed
US-4824951-A MUSCLE RELAXANTS, ANTICONVULSANTS, ANXIOLYTIC AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1989-04-25 US disclosed
US-4772600-A MUSCLE RELAXANTS, ANTICONVULSANTS, ANXIOLYTIC A. H. ROBINS COMPANY, INC. (US) 1988-09-20 US disclosed
EP-0255217-A1 Fused imidazoheterocyclic compounds A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) 1988-02-03 EP disclosed