Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566844 | 0.87 | MEN1 (0.40) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL6733075 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8562112 | 0.79 | GAA (0.41) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL4457346 | 0.78 | MAPT (0.50) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL17555458 | 0.78 | ALDH1A1 (0.36) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8569930 | 0.78 | MEN1 (0.35) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL16026726 | 0.78 | TSHR (0.44) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8563757 | 0.73 | ALDH1A1 (0.40) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8568327 | 0.73 | MEN1 (0.39) | ALDH1A1MEN1KMT2AUSP2KEAP1 | |
| SCHEMBL8560493 | 0.73 | ALDH1A1 (0.38) | MAPTALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |