⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518830 | 0.74 | KDM5B (0.50) | — | |
| SCHEMBL8498231 | 0.73 | — | — | |
| SCHEMBL3073644 | 0.71 | — | — | |
| SCHEMBL3235103 | 0.69 | — | — | |
| SCHEMBL12148282 | 0.69 | ALOX15 (0.46) | — | |
| SCHEMBL2169712 | 0.69 | — | — | |
| SCHEMBL26832 | 0.69 | — | — | |
| SCHEMBL15848225 | 0.69 | — | — | |
| SCHEMBL10345081 | 0.69 | — | — | |
| SCHEMBL6901007 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040230072-A1 | Phosphodiesterase 4 inhibitors | SCHUMACHER RICHARD A (US) | 2004-11-18 | — | — | US | claimed |
| EP-1353907-A2 | PHOSPHODIESTERASE 4 INHIBITORS | Memory Pharmaceutical Corporation (US) | 2003-10-22 | — | — | EP | claimed |
| US-20030149052-A1 | Phosphodiesterase 4 inhibitors | MEMORY PHARMACEUTICALS CORP. | 2003-08-07 | — | — | US | claimed |
| US-20020151566-A1 | Phosphodiesterase 4 inhibitors | MEMORY PHARMACEUTICALS CORP. (US) | 2002-10-17 | — | — | US | claimed |
| WO-2002074726-A2 | ANILINE DERIVATIVES USEFUL AS PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2002-09-26 | — | — | WO | claimed |
| CN-110799866-B | Optical film | 住友化学株式会社 | 2022-05-27 | — | — | CN | disclosed |
| CN-105907316-B | Method for manufacturing optical component with resin film | 住友化学株式会社 | 2021-08-10 | — | — | CN | disclosed |