Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734212 | 0.80 | MAPT (0.44) | ALDH1A1MAPTHPGDNPC1RAB9A | |
| SCHEMBL4061067 | 0.73 | ALDH1A1 (0.55) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL29736247 | 0.73 | ALDH1A1 (0.55) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL4764227 | 0.70 | KDM1A (0.42) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL14389682 | 0.70 | MEN1 (0.70) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL16316247 | 0.70 | PDE4A (0.47) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL16871023 | 0.70 | MEN1 (0.70) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL17525544 | 0.69 | MAPT (0.50) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL980277 | 0.68 | NTRK1 (0.58) | KITNTRK1MEN1KMT2AKDM4E | |
| SCHEMBL15684033 | 0.68 | MEN1 (0.73) | MEN1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110757-A1 | Flt-1 ligands and their uses in the treatment of diseases regulatable by angiogenesis | ARRHENIUS THOMAS (US) | 2004-06-10 | — | — | US | disclosed |
| EP-1370250-A2 | FLT-1 LIGANDS AND THEIR USES IN THE TREATMENT OF DISEASES REGULATABLE BY ANGIOGENESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002076438-A2 | FLT-1 LIGANDS AND THEIR USES IN THE TREATMENT OF DISEASES REGULATABLE BY ANGIOGENESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110757-A1 | Flt-1 ligands and their uses in the treatment of diseases regulatable by angiogenesis | FLT1, FLT4, TEK | KIT 57/4885NTRK1 338/4885MEN1 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.