Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.74 |
| ▸ | TK2 | O00142 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6733504 | 1.00 | TK1 (0.74) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL8165629 | 0.99 | TK1 (0.73) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL4205795 | 0.99 | TK1 (0.73) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL8165631 | 0.99 | TK1 (0.73) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL888210 | 0.97 | TK1 (0.76) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL532244 | 0.97 | TK1 (0.76) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL31490225 | 0.92 | TK1 (0.79) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL17456217 | 0.91 | TK1 (0.78) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL17456218 | 0.91 | TK1 (0.78) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL1679403 | 0.89 | TK1 (0.85) | TK1TK2LMNASMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38416-E1 | NUCLEOTIDE BASES COMPRISING PYRAZOLO(3,4-D)PYRIMIDINES USED FOR MEDICAL DIAGNOSIS, THERAPY, HYBRIDIZATION, ANTISENSE AGENTS OR REPORTER MOLECULES | EPOCH BIOSCIENCES, INC. | 2004-02-03 | — | — | US | disclosed |
| US-5849482-A | Crosslinking oligonucleotides | EPOCH PHARMACEUTICALS, INC. (US) | 1998-12-15 | — | — | US | disclosed |
| US-5824796-A | MEDICAL DIAGNOSIS WITH TARGET DNA OR RNA FOR ENZYME INHIBITORS | EPOCH PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |
| EP-0842186-A1 | CROSS-LINKING OLIGONUCLEOTIDES | MICROPROBE CORPORATION (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1993003736-A1 | CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION | MICROPROBE CORPORATION (US) | 1993-03-04 | — | — | WO | disclosed |