Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.76 |
| ▸ | TK2 | O00142 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888210 | 1.00 | TK1 (0.76) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL6733504 | 0.97 | TK1 (0.74) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL6733500 | 0.97 | TK1 (0.74) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL4205795 | 0.96 | TK1 (0.73) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL8165631 | 0.96 | TK1 (0.73) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL8165629 | 0.96 | TK1 (0.73) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL31490225 | 0.93 | TK1 (0.79) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL17456218 | 0.90 | TK1 (0.78) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL17456217 | 0.90 | TK1 (0.78) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL7875550 | 0.90 | TK1 (0.68) | TK1TK2LMNASMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465921-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2013-06-18 | — | — | US | disclosed |
| EP-1430147-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2013-05-22 | — | — | EP | disclosed |
| EP-1235938-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2012-02-08 | — | — | EP | disclosed |
| US-20110275070-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH PHARMACEUTICALS, INC. | 2011-11-10 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-7794945-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2010-09-14 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-7662942-B2 | Oligonucleotide probes containing two labels useful in hybridization assays | Elitech Holdings, B.V. (NL) | 2010-02-16 | — | — | US | disclosed |
| US-7556923-B1 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | EPOCH BIOSCIENCES, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| WO-2009058852-A2 | MINOR GROOVE BINDER-ENERGY TRANSFER OLIGONUCLEOTIDES AND METHODS FOR THEIR USE | EPOCH BIOSCIENCES, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| EP-0159719-B1 | HYBRIDIZATION METHOD FOR THE DETECTION OF GENETIC MATERIALS | ENZO BIOCHEM, INC. (US) | 1993-06-30 | — | — | EP | disclosed |
| EP-0547142-A1 | SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE | EPOCH PHARMACEUTICALS, INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1993003736-A1 | CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION | MICROPROBE CORPORATION (US) | 1993-03-04 | — | — | WO | disclosed |
| EP-0526912-A2 | Methods and compositions for the detection of a single-stranded target genetic material | ENZO BIOCHEM, INC. (US) | 1993-02-10 | — | — | EP | disclosed |
| EP-0472648-A4 | CROSSLINKING OLIGONUCLEOTIDES | — | 1992-09-16 | — | — | EP | disclosed |
| WO-1992003464-A1 | SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE | MICROPROBE CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |
| EP-0472648-A1 | CROSSLINKING OLIGONUCLEOTIDES | MICROPROBE CORPORATION (US) | 1992-03-04 | — | — | EP | disclosed |
| WO-1990014353-A1 | CROSSLINKING OLIGONUCLEOTIDES | MICROPROBE CORPORATION (US) | 1990-11-29 | — | — | WO | disclosed |
| US-4894325-A | Hybridization method for the detection of genetic material | ENZO BIOCHEM, INC. (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0159719-A2 | Hybridization method for the detection of genetic materials | ENZO BIOCHEM, INC. (US) | 1985-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | DDX5, DDX21, DCLRE1B | TK1 1043/4885TK2 1386/4885LMNA 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.