SCHEMBL673353

SCHEMBL673353

Brc1ccc(-c2ccccc2Br)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.71
ALDH1A1 P00352 4/20 0.71
NPC1 O15118 7/20 0.57
RAB9A P51151 7/20 0.57
SMN1; SMN2 Q16637 6/20 0.57
MAPT P10636 3/20 0.57
TP53 P04637 3/20 0.57
TSHR P16473 2/20 0.57
HPGD P15428 1/20 0.57
PTPRC P08575 1/20 0.45
SLC6A3 Q01959 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
CYP2A6 P11509 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
PLK4 O00444 1/20 0.39
AURKA O14965 1/20 0.39
JAK2 O60674 1/20 0.39
LCK P06239 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31321399 0.97 MAPK1 (0.68) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL12489603 0.92 ALDH1A1 (0.83) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL11528731 0.87 ALDH1A1 (0.56) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL7522172 0.86 ALDH1A1 (0.63) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL19125933 0.86 ALDH1A1 (0.63) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL3778039 0.84 ALDH1A1 (0.90) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL30121160 0.84 ALDH1A1 (0.90) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL30451936 0.83 ALDH1A1 (1.00) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL115115 0.83 ALDH1A1 (1.00) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
Methane SCHEMBL10434104 0.81 ALDH1A1 (0.94) MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1015 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10066056-B2 Brominated cross-linkable polycarbonate compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-09-04 US claimed
US-20170129996-A1 BROMINATED CROSS-LINKABLE POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-05-11 US claimed
WO-2015193859-A1 BROMINATED CROSS-LINKABLE POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-12-23 WO claimed
US-8975367-B2 Polyphosphonate and copolyphosphonate additive mixtures FRX POLYMERS, INC. (US) 2015-03-10 US claimed
EP-2697309-A2 POLYPHOSPHONATE AND COPOLYPHOSPHONATE ADDITIVE MIXTURES FRX Polymers, Inc. (US) 2014-02-19 EP claimed
US-20120264844-A1 POLYPHOSPHONATE AND COPOLYPHOSPHONATE ADDITIVE MIXTURES FRX POLYMERS, INC. (US) 2012-10-18 US claimed
WO-2012142596-A2 POLYPHOSPHONATE AND COPOLYPHOSPHONATE ADDITIVE MIXTURES FRX POLYMERS, INC. (US) 2012-10-18 WO claimed
EP-1045759-B1 MULTILAYER FILMS HAVING AT LEAST FIVE FILM LAYERS, WHEREIN AT LEAST ONE LAYER IS FLAME RETARDANT MINNESOTA MINING & MFG (US) 2006-10-25 EP claimed
US-5357027-A Fireproof, heat resistant, impact resistant molding materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-10-18 US claimed
US-4340768-A COPPER CATALYZED HYDROLYSIS OF 4,4*-DIBROMO BIPHENYL HODOGAYA CHEMICAL CO., LTD. (JP) 1982-07-20 US claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER SHPP GLOBAL TECH B V (NL) 2026-05-14 US disclosed
EP-4720194-A1 POLYCARBONATE COPOLYMER COMPOSITIONS SHPP Global Technologies B.V. (NL) 2026-04-08 EP disclosed
EP-4605473-B1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECH BV (NL) 2026-04-01 EP disclosed
EP-4716968-A1 BATTERY PACK COVER WITH A PROTRUDING DOUBLE WALL BATTERY DIVIDER AND THERMAL RUNAWAY BARRIER SABIC Global Technologies B.V. (NL) 2026-04-01 EP disclosed
US-3974235-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and flame retardant GENERAL ELECTRIC COMPANY (US) 1976-08-10 US disclosed
US-3959211-A ETHYLENE-ALPHA-OLEFIN-DIENE GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed
US-3953394-A POLYETHYLENE TEREPHTHALATE-POLYBUTYLENE TEREPHTHALATE BLENDS GENERAL ELECTRIC COMPANY (US) 1976-04-27 US disclosed
US-3950301-A HYDROXYBENZOTRIAZOLES, FIREPROOFING GENERAL ELECTRIC COMPANY (US) 1976-04-13 US disclosed
US-3943191-A MOLDING GENERAL ELECTRIC COMPANY (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION CYP46A1, RPTOR, PCNA MAPK1 3756/4885ALDH1A1 3743/4885NPC1 176/4885
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER CBLB, UBE4A, PSMD14 MAPK1 130/4885ALDH1A1 1440/4885NPC1 4864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.