SCHEMBL673360

SCHEMBL673360

C=CC(=O)OC1(C(C)C)CC1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.41
HPGD P15428 1/20 0.31
ALDH1A1 P00352 3/20 0.30
TP53 P04637 2/20 0.30
HIF1A Q16665 2/20 0.30
CYP3A4 P08684 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL8364683 0.94 TSHR (0.37) TSHR
SCHEMBL263898 0.92 TSHR (0.38) TSHR
SCHEMBL684980 0.90 TSHR (0.37) TSHR
SCHEMBL684954 0.90 TSHR (0.37) TSHR
SCHEMBL686092 0.90 TSHR (0.37) TSHR
Methacrylic Acid SCHEMBL5177816 0.89 TSHR (0.34) TSHR
SCHEMBL11842327 0.86 TSHR (0.39) TSHRHPGD
SCHEMBL4807624 0.86 TSHR (0.34) TSHR
SCHEMBL4406127 0.82 TSHR (0.35) TSHRHPGDALDH1A1
SCHEMBL16192129 0.82 EP300 (0.30) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4440996-B2 2010-03-24 JP claimed
WO-2008042170-A1 COMPOSITION COMPRISING ETHYLENE COPOLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-10 WO claimed
US-20080081861-A1 Composition comprising ethylene copolymer E. I. DU PONT DE NEMOURS AND COMPANY 2008-04-03 US claimed
US-7199180-B1 Adhesives comprising olefin polymers THE DOW CHEMICAL COMPANY (US) 2007-04-03 US claimed
EP-0886656-B1 ADHESIVES COMPRISING OLEFIN POLYMERS DOW CHEMICAL CO (US) 2001-09-19 EP claimed
JP-2000507283-A 2000-06-13 JP claimed
EP-0886656-A1 ADHESIVES COMPRISING OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1998-12-30 EP claimed
WO-1997033921-A1 ADHESIVES COMPRISING OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-09-18 WO claimed
EP-0084355-B1 ORGANIC ACID CONTAINING FILLED AND PLASTICIZED THERMOPLASTIC COMPOSITIONS BASED ON ETHYLENE INTERPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-06 EP claimed
EP-0100066-B1 SURFACTANT-CONTAINING FILLED AND PLASTICIZED THERMOPLASTIC COMPOSITIONS BASED ON ETHYLENE INTERPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-03-12 EP claimed
EP-0101028-A1 Extrudable self-supporting hot melt adhesive sheet E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-22 EP claimed
EP-0100066-A1 Surfactant-containing filled and plasticized thermoplastic compositions based on ethylene interpolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-08 EP claimed
US-4430468-A SOUND DEADENING COATINGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-07 US claimed
US-4403007-A POLYMER BLENDS, ACOUSTICAL DAMPENING E. I. DU PONT DE NEMOURS & CO. (US) 1983-09-06 US claimed
EP-0084355-A1 Organic acid containing filled and plasticized thermoplastic compositions based on ethylene interpolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-27 EP claimed
US-4379190-A Filled thermoplastic compositions based on mixtures of ethylene interpolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-04-05 US claimed
EP-0045967-A2 Filled thermoplastic compositions based on mixtures of ethylene interpolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-02-17 EP claimed
US-4263196-A COATING FOR ACOUSTICALLY INSULATING AUTOMOTIVE CARPET E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-04-21 US claimed
US-4191798-A Highly filled thermoplastic compositions based on ethylene interpolymers and processing oils E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-03-04 US claimed
US-3988509-A Reduced melt index, low gel content ethylene copolymers and process for preparation thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-10-26 US claimed