SCHEMBL263898

SCHEMBL263898

C=CC(=O)OC1(C(C)C)CCCC1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686092 0.98 TSHR (0.37) TSHR
SCHEMBL684980 0.98 TSHR (0.37) TSHR
SCHEMBL684954 0.98 TSHR (0.37) TSHR
SCHEMBL673360 0.92 TSHR (0.41) TSHR
Acrylic Acid SCHEMBL8364683 0.87 TSHR (0.37) TSHR
SCHEMBL8106024 0.84 HCAR2 (0.33)
SCHEMBL8102011 0.82 HCAR2 (0.32)
Methacrylic Acid SCHEMBL5177816 0.82 TSHR (0.34) TSHR
SCHEMBL4399278 0.82 TSHR (0.38) TSHR
SCHEMBL4807624 0.82 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565554-B2 Dual-phase zwitterionic monomers KUNZLER BIOMEDICAL LLC (US) 2026-03-03 US disclosed
US-12510690-B2 Ophthalmic devices BAUSCH + LOMB IRELAND LIMITED (IE) 2025-12-30 US disclosed
US-20250326873-A1 DUAL-PHASE ZWITTERIONIC MONOMERS Envision Biomedical LLC (US) 2025-10-23 US disclosed
US-12371519-B2 Dual-phase zwitterionic monomers Envision Biomedical LLC (US) 2025-07-29 US disclosed
WO-2025094825-A1 HETEROPOLYOXOMETALATE HAVING MODIFIED LACUNARY SITE, OR MIXTURE THEREOF 東京応化工業株式会社 2025-05-08 WO disclosed
US-20250092174-A1 DUAL-PHASE ZWITTERIONIC MONOMERS Envision Biomedical LLC (US) 2025-03-20 US disclosed
EP-4483218-A1 OPHTHALMIC DEVICES Bausch + Lomb Ireland Limited (IE) 2025-01-01 EP disclosed
US-12054590-B2 Hydrogel polymers GL CHEMTEC VISION INC. (CA) 2024-08-06 US disclosed
US-11905351-B2 Silicone hydrogel materials Envision Biomedical LLC (US) 2024-02-20 US disclosed
US-20240026049-A1 DUAL-PHASE ZWITTERIONIC MONOMERS Envision Biomedical LLC (US) 2024-01-25 US disclosed
EP-0338656-B1 Polymeric silicone-based materials with high oxygen permeability BAUSCH & LOMB (US) 1994-03-02 EP disclosed
EP-0328340-B1 HYDROPHILIC OXYGEN PERMEABLE POLYMERS BAUSCH & LOMB INCORPORATED (US) 1993-03-31 EP disclosed
US-4910277-A Blend of polysiloxane and an interior wetting agent BAUSCH & LOMB INCORPORATED 1990-03-20 US disclosed
EP-0338656-A2 Polymeric silicone-based materials with high oxygen permeability BAUSCH & LOMB INCORPORATED (US) 1989-10-25 EP disclosed
US-4870145-A Process for preparing polymeric beads BAUSCH & LOMB INCORPORATED (US) 1989-09-26 US disclosed
EP-0328340-A2 Hydrophilic oxygen permeable polymers BAUSCH & LOMB INCORPORATED (US) 1989-08-16 EP disclosed
EP-0124017-B1 POLYSILOXANE COMPOSITION WITH IMPROVED SURFACE WETTING CHARACTERISTICS AND BIOMEDICAL DEVICES MADE THEREOF BAUSCH & LOMB INCORPORATED (US) 1989-07-26 EP disclosed
US-4810764-A CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1989-03-07 US disclosed
US-4652622-A CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1987-03-24 US disclosed
US-4495361-A N-ALKENOYL TRIALKYSILYL AMINATE BAUSCH & LOMB INCORPORATED (US) 1985-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092174-A1 DUAL-PHASE ZWITTERIONIC MONOMERS RAD1, RAD51, VCL TSHR 3440/4885
US-12510690-B2 Ophthalmic devices AXL, SLCO1B1, SLCO1B3 TSHR 1414/4885
US-12565554-B2 Dual-phase zwitterionic monomers HAO2, CRYZ, CRYAA TSHR 1764/4885
US-20250326873-A1 DUAL-PHASE ZWITTERIONIC MONOMERS RAD1, RAD51, VCL TSHR 3440/4885
US-20240026049-A1 DUAL-PHASE ZWITTERIONIC MONOMERS RAD1, RAD51, VCL TSHR 3440/4885
US-12371519-B2 Dual-phase zwitterionic monomers RAD1, RAD51, VCL TSHR 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.