SCHEMBL673415

SCHEMBL673415

Cc1cccc2c1sc1nncn12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 18/20 1.00
PARP15 Q460N3 17/20 1.00
PARP2 Q9UGN5 17/20 1.00
PARP10 Q53GL7 15/20 1.00
BRPF1 P55201 1/20 0.58
PARP14 Q460N5 2/20 0.50
TNKS O95271 1/20 0.43
PARP1 P09874 1/20 0.43
PARP11 Q9NR21 1/20 0.43
PARP4 Q9UKK3 1/20 0.43
PARP3 Q9Y6F1 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25323644 0.80 TNKS2 (1.00) TNKS2PARP15PARP2PARP10BRPF1
SCHEMBL25324686 0.74 TNKS2 (1.00) TNKS2PARP15PARP2PARP10BRPF1
Tricyclazole SCHEMBL23082 0.73 BRPF1 (1.00) TNKS2PARP15PARP2PARP10BRPF1
Tricyclazole SCHEMBL14721539 0.73 BRPF1 (1.00) TNKS2PARP15PARP2PARP10BRPF1
SCHEMBL2489012 0.72 TNKS2 (1.00) TNKS2PARP15PARP2PARP10BRPF1
SCHEMBL25324694 0.71 TNKS2 (0.78) TNKS2PARP15PARP2PARP10BRPF1
SCHEMBL11748893 0.69 TNKS2 (0.66) TNKS2PARP15PARP2PARP10BRPF1
SCHEMBL11653477 0.68 PARP15 (0.51) TNKS2PARP15PARP2PARP10SMN1; SMN2
SCHEMBL25322717 0.68 TNKS2 (0.57) TNKS2PARP15PARP2PARP10BRPF1
SCHEMBL11651025 0.67 PARP15 (0.50) TNKS2PARP15PARP2PARP10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160841-B2 Uniformly spreadable granular agricultural chemicals formulation and method for scattering (applying) thereof KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-01-09 US claimed
US-20020133846-A1 Method for protecting plants RYALS JOHN ANDREW (US) 2002-09-19 US claimed
EP-0779030-B1 Plant protecting agents SYNGENTA PARTICIPATIONS AG (CH) 2001-07-18 EP claimed
EP-1009838-A2 METHOD FOR PROTECTING PLANTS Novartis AG (CH) 2000-06-21 EP claimed
US-6031153-A APPLYING A MICROBICIDE TO AN IMMUNOMODULATED GENETICALLY ENGINEERED PLANT FOR SYNERGISTIC DISEASE RESISTANCE NOVARTIS AG (CH) 2000-02-29 US claimed
EP-0900017-A1 PESTICIDAL COMPOSITIONS Novartis AG (CH) 1999-03-10 EP claimed
WO-1998029537-A2 METHOD FOR PROTECTING PLANTS NOVARTIS AG (CH) 1998-07-09 WO claimed
WO-1997040683-A1 PESTICIDAL COMPOSITIONS NOVARTIS AG (CH) 1997-11-06 WO claimed
EP-0280289-B1 STABILIZED SOLID COMPOSITION Takeda Chemical Industries, Ltd. (JP) 1992-07-29 EP claimed
EP-0281911-A2 Stabilized composition Takeda Chemical Industries, Ltd. (JP) 1988-09-14 EP claimed
EP-0280289-A2 Stabilized solid composition Takeda Chemical Industries, Ltd. (JP) 1988-08-31 EP claimed
JP-61087605-A None JP disclosed
JP-61109703-A None JP disclosed
JP-56169604-A None JP disclosed
JP-61152606-A None JP disclosed
JP-S5566504-A AGRICULTURAL AND HORTICULTURAL FUNGICIDE COMPOSITION KUMIAI CHEM IND CO LTD 1980-05-20 JP disclosed
JP-S05566504-A 0001-01-01 JP disclosed
JP-S05793986-A 0001-01-01 JP disclosed
JP-S05793986-A 0001-01-01 JP disclosed
JP-H00347106-A 0001-01-01 JP disclosed