SCHEMBL6734223

SCHEMBL6734223

O=C(c1cnc(-c2ccncc2)nc1)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.64
F10 P00742 13/20 0.60
SMN1; SMN2 Q16637 2/20 0.57
LMNA P02545 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.54
GAA P10253 1/20 0.53
F2 P00734 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5734823 0.89 ATM (0.60) ATMF10SMN1; SMN2LMNAL3MBTL1
SCHEMBL5193868 0.89 ATM (0.71) ATMF10SMN1; SMN2LMNAL3MBTL1
SCHEMBL6728415 0.89 LMNA (0.57) ATMF10SMN1; SMN2LMNAL3MBTL1
SCHEMBL6730880 0.88 F10 (0.53) ATMF10SMN1; SMN2LMNAL3MBTL1
Hydrochloric Acid SCHEMBL6195419 0.88 ATM (0.69) ATMF10SMN1; SMN2LMNAL3MBTL1
SCHEMBL5734538 0.87 F10 (0.55) ATMF10SMN1; SMN2LMNAL3MBTL1
SCHEMBL6733613 0.86 F10 (0.60) ATMF10SMN1; SMN2LMNAL3MBTL1
SCHEMBL6577783 0.84 SMN1; SMN2 (0.59) ATMF10SMN1; SMN2LMNAL3MBTL1
SCHEMBL6725501 0.84 SMN1; SMN2 (0.60) ATMF10SMN1; SMN2LMNAL3MBTL1
SCHEMBL6729881 0.83 F10 (0.58) ATMF10SMN1; SMN2LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 ATM 2080/4885F10 19/4885SMN1; SMN2 1510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.