Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.82 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.82 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.77 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.74 |
| ▸ | PIM1 | P11309 | 1/20 | 0.67 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.65 |
| ▸ | IGF1R | P08069 | 5/20 | 0.65 |
| ▸ | CDK2 | P24941 | 3/20 | 0.60 |
| ▸ | INSR | P06213 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734824 | 1.00 | HSPD1 (0.82) | HSPD1HSPE1PIK3CGPIK3CAPIM1 | |
| SCHEMBL1063990 | 0.88 | PIK3CG (0.65) | HSPD1HSPE1PIK3CGPIK3CAIGF1R | |
| SCHEMBL1063989 | 0.88 | PIK3CG (0.65) | HSPD1HSPE1PIK3CGPIK3CAIGF1R | |
| SCHEMBL14262656 | 0.88 | PIK3CG (0.65) | HSPD1HSPE1PIK3CGPIK3CAIGF1R | |
| SCHEMBL13388891 | 0.87 | PIK3CG (0.73) | HSPD1HSPE1PIK3CGPIK3CASIRT2 | |
| SCHEMBL4978943 | 0.87 | PIK3CG (1.00) | HSPD1HSPE1PIK3CGPIK3CAPIM1 | |
| SCHEMBL4978949 | 0.87 | PIK3CG (1.00) | HSPD1HSPE1PIK3CGPIK3CAPIM1 | |
| SCHEMBL3363802 | 0.86 | IGF1R (0.80) | HSPD1HSPE1PIK3CGPIK3CAIGF1R | |
| SCHEMBL1064250 | 0.86 | IGF1R (0.80) | HSPD1HSPE1PIK3CGPIK3CAIGF1R | |
| SCHEMBL1064248 | 0.86 | IGF1R (0.80) | HSPD1HSPE1PIK3CGPIK3CAIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002526-A1 | Phospholipase D inhibitors and uses thereof | CELL THERAPEUTICS, INC. | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002526-A1 | Phospholipase D inhibitors and uses thereof | PLD2, PLD1, PLA2G2D | HSPD1 1173/4885HSPE1 2501/4885PIK3CG 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.