SCHEMBL6734879

SCHEMBL6734879

CCCCc1ccc2cc3cc(F)c(F)c(F)c3cc2c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
BDKRB2 P30411 1/20 0.36
HTR1A P08908 1/20 0.35
BCHE P06276 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
PSMB5 P28074 1/20 0.35
TLR8 Q9NR97 6/20 0.34
GRIN2D O15399 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6736230 1.00 SKP2 (0.37) SKP2SIGMAR1BDKRB2HTR1ABCHE
SCHEMBL6741483 0.96 HTR2A (0.39) BDKRB2HTR1ATLR8
SCHEMBL6737669 0.91 CNR1 (0.39) SIGMAR1BDKRB2CYP1A2CYP2A6GRIN2D
SCHEMBL6738566 0.91 CNR1 (0.39) SIGMAR1BDKRB2CYP1A2CYP2A6GRIN2D
SCHEMBL6731145 0.87 SKP2 (0.43) SKP2SIGMAR1BDKRB2BCHECYP1A2
SCHEMBL6736893 0.87 TLR8 (0.39) SKP2SIGMAR1BDKRB2HTR1ABCHE
SCHEMBL6735680 0.86 CYP1A2 (0.48) BDKRB2HTR1ACYP1A2CYP2A6
SCHEMBL6736398 0.86 CYP1A2 (0.48) BDKRB2HTR1ACYP1A2CYP2A6
SCHEMBL6741609 0.86 SKP2 (0.36) SKP2SIGMAR1BDKRB2HTR1ABCHE
SCHEMBL6736335 0.86 SKP2 (0.36) SKP2SIGMAR1BDKRB2HTR1ABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6682785-B2 A FLUOROANTHRACENE COMPOUNDS; HEAT RESISTANCE, RADIATION RESISTANCE, PHOTOSTABILITY CLARIANT FINANCE (BVI) LIMITED (VG) 2004-01-27 US disclosed
US-20030118749-A1 A fluoroanthracene compounds; heat resistance, radiation resistance, photostability CLARIANT INTERNATIONAL LTD. 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118749-A1 A fluoroanthracene compounds; heat resistance, radiation resistance, photostability HSF1, ABCC1, FLNA SKP2 394/4885SIGMAR1 3306/4885BDKRB2 3182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.